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Updated: Feb 14, 2026

Y-27632 Enriches the Yield of Human Melanocytes from Adult Skin Tissues
Published on: July 8, 2020
A pediatric case of unusual melanocytic proliferation of the nail
Regine J Mathieu1, Marjon Vatanchi, Edward R Heilman
1New York Medical College, Valhalla, New York. rjmmathieu@gmail.com.
Abstract:
Pigmentation of the nail plate, or melanonychia, is typically a benign condition caused by melanocyte activation. Although rare, melanonychia may be the initial presentation of melanoma, thus all cases require an in-depth examination. Evaluation in pediatric patients can prove especially difficult as benign cases have a higher prevalence of atypia compared to adults. Lack of specific treatment guidelines in the pediatric population can make diagnosis and treatment challenging. We report a pediatric patient with melanonychia with atypical features that required significant evaluations and collaboration to ultimately reach a treatment plan.
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