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Clinical resolution of pemphigus vulgaris on rituximab

Elizabeth Cusick1, David Silverstein

  • 1Department of Dermatology, Stony Brook University School of Medicine, New York, New York.

Dermatology Online Journal
|February 23, 2018
PubMed

Although significant progress has been made for the treatment of pemphigus vulgaris (PV) with rituximab (RTX), a consensus remains to be determined for standard treatment protocol, regarding optimal dosing, infusion regimen, and use of concomitant immunotherapy to achieve safe, effective, and rapid clinical response. We describe a patient with pemphigus vulgaris treated with high dose rituximab with the rheumatoid arthritis protocol along with intravenous immunoglobulin therapy. This case provides evidence towards the growing body of research needed to modify and improve treatment for pemphigus using rituximab.

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