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Updated: Feb 14, 2026
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Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
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[Lymph-node-positive penile cancer : Management and systemic therapy].
A Aziz1, S Milerski2, K Kernig2
1Klinik und Poliklinik für Urologie, Universitätsmedizin Rostock, Schillingallee 35, 18057, Rostock, Deutschland. Atiqullah.Aziz@med.uni-rostock.de.
Der Urologe. Ausg. A
|February 23, 2018
Summary
Penile cancer survival is determined by lymph node metastasis extent. Limited inguinal spread offers up to 80% 5-year survival, while pelvic or systemic disease drastically reduces prognosis to 0-33%.
Area of Science:
- Oncology
- Urology
Background:
- Penile cancer survival is significantly impacted by lymph node metastasis.
- The extent of metastasis, specifically to inguinal and pelvic lymph nodes, is a critical prognostic factor.
Purpose of the Study:
- To analyze the impact of regional lymphatic metastasis on cancer-specific survival in penile cancer patients.
- To highlight the prognostic significance of lymph node involvement in penile cancer management.
Main Methods:
- Survival analysis based on the extent of lymph node metastasis (inguinal vs. pelvic).
- Review of patient data correlating metastasis patterns with 5-year survival rates.
Main Results:
- Limited inguinal lymph node metastases are associated with a 5-year survival of up to 80%.
- Pelvic lymph node metastases and/or systemic disease significantly decrease 5-year survival to 0-33%.
Conclusions:
- The extent of regional lymphatic metastasis is the primary determinant of cancer-specific survival in penile cancer.
- Multimodal treatment, including complete lymphadenectomy and adjuvant chemotherapy, is indicated for patients with regional lymph node metastases.
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