Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

The Evidence for Evolution02:55

The Evidence for Evolution

48.4K
Genetic variations accumulating within populations over generations give rise to biological evolution. Evolutionary changes can result in the formation of novel varieties and entire new species. These changes are responsible for the diverse forms of life inhabiting the planet. The evidence for evolution suggests that all living organisms descended from common ancestors.
48.4K
Convergent Evolution01:54

Convergent Evolution

33.1K
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
33.1K
Eukaryotic Evolution01:24

Eukaryotic Evolution

42.5K
The endosymbiont theory is the most widely accepted theory of eukaryotic evolution; however, its progression is still somewhat debated. According to the nucleus-first hypothesis, the ancestral prokaryote first evolved a membrane to enclose DNA and form the nucleus. Conversely, the mitochondria-first hypothesis suggests that the nucleus was formed after endosymbiosis of mitochondria.
Contrary to the endosymbiont theory, the eukaryote-first hypothesis proposes that the simpler prokaryotic and...
42.5K
Synteny and Evolution02:31

Synteny and Evolution

3.8K
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
3.8K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

3.7K
3.7K
Gene Evolution - Fast or Slow?02:05

Gene Evolution - Fast or Slow?

8.2K
The genomes of eukaryotes are punctuated by long stretches of sequence which do not code for proteins or RNAs. Although some of these regions do contain crucial regulatory sequences, the vast majority of this DNA serves no known function. Typically, these regions of the genome are the ones in which the fastest change, in evolutionary terms, is observed, because there is typically little to no selection pressure acting on these regions to preserve their sequences.
In contrast, regions which code...
8.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early transcription factor activation distinguishes symbiotic from non-symbiotic bacteria during microbiome processing in a sponge.

The ISME journal·2026
Same author

Experimental Evidence for a Metal-Related Function of a Cyanobactin.

Angewandte Chemie (International ed. in English)·2026
Same author

Transcriptomic responses to Marteilia sydneyi infection in the sydney rock oyster Saccostrea glomerata.

Fish & shellfish immunology·2025
Same author

A modified primer-pair designed for the molecular sex identification of black-legged Kittiwake (Laridae: <i>Rissa tridactyla</i>).

Conservation genetics resources·2025
Same author

2025 joint BMC ecology and evolution and BMC zoology image competition: the winning images.

BMC ecology and evolution·2025
Same author

Sponge bHLH Gene Expression in <i>Xenopus laevis</i> Disrupts Inner Ear and Lateral Line Neurosensory Development and Otic Afferent Pathfinding.

International journal of molecular sciences·2025
Same journal

Zebrafish models of acute leukemias: Current models and future directions.

Wiley interdisciplinary reviews. Developmental biology·2020
Same journal

Schwann cell development: From neural crest to myelin sheath.

Wiley interdisciplinary reviews. Developmental biology·2020
Same journal

Human pluripotent stem cell-derived lung organoids: Potential applications in development and disease modeling.

Wiley interdisciplinary reviews. Developmental biology·2020
Same journal

The macro and micro of chromosome conformation capture.

Wiley interdisciplinary reviews. Developmental biology·2020
Same journal

Single-cell RNA sequencing in Drosophila: Technologies and applications.

Wiley interdisciplinary reviews. Developmental biology·2020
Same journal

Proximity-dependent labeling methods for proteomic profiling in living cells: An update.

Wiley interdisciplinary reviews. Developmental biology·2020
See all related articles

Related Experiment Video

Updated: Feb 14, 2026

Molecular Evolution of the Tre Recombinase
12:02

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

10.1K

The evolution of mollusc shells.

Carmel McDougall1, Bernard M Degnan1

  • 1Centre for Marine Sciences, School of Biological Sciences, The University of Queensland, Brisbane, Queensland, Australia.

Wiley Interdisciplinary Reviews. Developmental Biology
|February 23, 2018
PubMed
Summary
This summary is machine-generated.

Molluscan shell diversity arises from a rapidly evolving mantle secretome, driven by gene changes and unique protein domain recruitment. This explains the evolution of diverse shells and other animal biominerals.

Keywords:
biomineralizationco-optionevolutionmolluscshell

More Related Videos

Author Spotlight: Understanding Microbe Adaptation Using Innovative Techniques for Exploring Thermophilic Evolution
08:11

Author Spotlight: Understanding Microbe Adaptation Using Innovative Techniques for Exploring Thermophilic Evolution

Published on: June 14, 2024

1.4K
Author Spotlight: Advancing Protein Engineering &#8211; Harnessing Evolution Through PRANCE and Lab Automation
05:08

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation

Published on: January 12, 2024

2.3K

Related Experiment Videos

Last Updated: Feb 14, 2026

Molecular Evolution of the Tre Recombinase
12:02

Molecular Evolution of the Tre Recombinase

Published on: May 29, 2008

10.1K
Author Spotlight: Understanding Microbe Adaptation Using Innovative Techniques for Exploring Thermophilic Evolution
08:11

Author Spotlight: Understanding Microbe Adaptation Using Innovative Techniques for Exploring Thermophilic Evolution

Published on: June 14, 2024

1.4K
Author Spotlight: Advancing Protein Engineering &#8211; Harnessing Evolution Through PRANCE and Lab Automation
05:08

Author Spotlight: Advancing Protein Engineering – Harnessing Evolution Through PRANCE and Lab Automation

Published on: January 12, 2024

2.3K

Area of Science:

  • Comparative Development and Evolution
  • Evolutionary Novelties
  • Regulation of Organ Diversity

Background:

  • Molluscan shells exhibit remarkable diversity, despite conserved genes for mantle progenitor cell specification.
  • The specific genes driving mature shell formation are highly variable across species.

Purpose of the Study:

  • To investigate the molecular basis of molluscan shell diversity.
  • To understand the role of the mantle secretome in shell evolution.

Main Methods:

  • Comparative analysis of mantle transcriptomes and shell proteomes in gastropods and bivalves.
  • Examination of gene regulatory networks and coding sequence evolution.

Main Results:

  • Shell diversity is underpinned by a rapidly evolving mantle secretome.
  • High rates of gene co-option/loss and rapid evolution of coding sequences, especially repetitive domains, contribute to secretome diversity.
  • Common protein domains (extracellular matrix, immunity) were independently co-opted into mantle secretomes.

Conclusions:

  • The evolvability of the mantle secretome provides a molecular explanation for molluscan shell diversity.
  • These genomic processes likely drive the evolution of other animal biominerals, such as coral and echinoderm skeletons.