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Related Experiment Video

Updated: Feb 14, 2026

Appetitive Associative Olfactory Learning in Drosophila Larvae
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A Spotlight on Appetite.

Lisa R Beutler1, Zachary A Knight2

  • 1Department of Medicine, University of California, San Francisco, San Francisco, CA 94158, USA.

Neuron
|February 23, 2018
PubMed
Summary
This summary is machine-generated.

The newly discovered hormone asprosin activates specific brain neurons to increase appetite and body weight. Asprosin represents a significant finding in understanding appetite regulation and energy balance.

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Area of Science:

  • Neuroendocrinology
  • Metabolism
  • Physiology

Background:

  • Hormonal regulation of appetite is crucial for energy balance.
  • Few hormones have been identified that stimulate appetite.
  • Understanding appetite-stimulating hormones is key to addressing metabolic disorders.

Purpose of the Study:

  • To highlight the discovery and function of asprosin.
  • To explain asprosin's role in activating AgRP neurons.
  • To underscore asprosin's impact on food intake and body weight.

Main Methods:

  • Literature review of recent discoveries in appetite regulation.
  • Analysis of studies identifying asprosin and its mechanisms.
  • Synthesis of findings on asprosin's effects on AgRP neurons.

Main Results:

  • Asprosin is a newly identified appetite-stimulating hormone.
  • Asprosin activates Agouti-related peptide (AgRP) neurons.
  • Activation of AgRP neurons by asprosin leads to increased food intake and body weight.

Conclusions:

  • Asprosin plays a significant role in stimulating appetite.
  • The discovery of asprosin fills a gap in understanding appetite-regulating hormones.
  • Asprosin offers a potential target for future research in metabolic and weight management.