Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Long-term Depression01:05

Long-term Depression

33.4K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
33.4K
Long-term Depression01:03

Long-term Depression

3.4K
Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over...
3.4K
Freezing Point Depression and Boiling Point Elevation03:12

Freezing Point Depression and Boiling Point Elevation

40.7K
Boiling Point Elevation
The boiling point of a liquid is the temperature at which its vapor pressure is equal to ambient atmospheric pressure. Since the vapor pressure of a solution is lowered due to the presence of nonvolatile solutes, it stands to reason that the solution’s boiling point will subsequently be increased. Vapor pressure increases with temperature, and so a solution will require a higher temperature than will pure solvent to achieve any given vapor pressure, including one...
40.7K
Depressants01:28

Depressants

474
Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
Alcohol is a common depressant that can induce a sense of relaxation and reduced inhibition at low doses. Contrary to its occasional...
474
Positive Symptoms of Schizophrenia: Hallucinations and Delusions01:30

Positive Symptoms of Schizophrenia: Hallucinations and Delusions

696
Schizophrenia is a complex mental health disorder that can manifest with various positive symptoms, including thought, movement, and behavior disorders. These symptoms significantly disrupt cognitive and motor functions, leading to profound effects on an individual's ability to engage with the world.
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
696
Positive Symptoms Schizophrenia: Hallucinations and Delusions01:26

Positive Symptoms Schizophrenia: Hallucinations and Delusions

633
Schizophrenia is a complex psychiatric disorder characterized by a range of symptoms that significantly impact cognition, behavior, and emotional regulation. Among these, the positive symptoms stand out as they involve the addition or exaggeration of normal mental functions, deviating markedly from typical behavior and perception. Hallucinations and delusions are prominent positive symptoms, each profoundly affecting the individual's experience of reality.
Hallucinations
Hallucinations in...
633

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of Cognitive Behavioral Therapy for Worry Versus Befriending Therapy in Individuals with Persecutory Delusions: A Randomized Trial.

Schizophrenia bulletin open·2026
Same author

Feasibility trial of the virtual reality application gameChange in a Norwegian psychosis participant group.

Nordic journal of psychiatry·2026
Same author

Helping Patients With Persecutory Delusions Find Safety.

Schizophrenia bulletin·2026
Same author

An excitement building in the development of psychological treatments for schizophrenia.

World psychiatry : official journal of the World Psychiatric Association (WPA)·2026
Same author

Patient expectations for outcome with psychological intervention for psychosis.

Schizophrenia research·2026
Same author

Triggering anger using a virtual reality social scene.

Scientific reports·2026

Related Experiment Video

Updated: Feb 14, 2026

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
07:27

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

10.9K

Schematic beliefs and problem solving performance predict depression in people experiencing persecutory delusions.

Natasha Vorontsova1, Philippa Garety1, Daniel Freeman2

  • 1King's College London, United Kingdom.

Journal of Psychiatric Research
|February 23, 2018
PubMed
Summary

Negative self-beliefs and poor problem-solving skills predict persistent depression in individuals with persecutory delusions. These factors contribute to the ongoing depression alongside psychosis, highlighting potential intervention targets.

Keywords:
DepressionLongitudinalPersecutory delusionsProblem solvingPsychosisSchematic beliefs

More Related Videos

Using Facial Electromyography to Assess Facial Muscle Reactions to Experienced and Observed Affective Touch in Humans
04:27

Using Facial Electromyography to Assess Facial Muscle Reactions to Experienced and Observed Affective Touch in Humans

Published on: March 15, 2019

11.9K
Experimental Research Examining How People Can Cope with Uncertainty Through Soft Haptic Sensations
09:07

Experimental Research Examining How People Can Cope with Uncertainty Through Soft Haptic Sensations

Published on: September 16, 2015

9.5K

Related Experiment Videos

Last Updated: Feb 14, 2026

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty
07:27

Exergaming in Older People Living with HIV Improves Balance, Mobility and Ameliorates Some Aspects of Frailty

Published on: October 6, 2016

10.9K
Using Facial Electromyography to Assess Facial Muscle Reactions to Experienced and Observed Affective Touch in Humans
04:27

Using Facial Electromyography to Assess Facial Muscle Reactions to Experienced and Observed Affective Touch in Humans

Published on: March 15, 2019

11.9K
Experimental Research Examining How People Can Cope with Uncertainty Through Soft Haptic Sensations
09:07

Experimental Research Examining How People Can Cope with Uncertainty Through Soft Haptic Sensations

Published on: September 16, 2015

9.5K

Area of Science:

  • Psychiatry
  • Clinical Psychology

Background:

  • Depression co-occurring with psychosis is a significant clinical issue.
  • It can maintain positive psychotic symptoms and requires effective treatment targets.
  • Understanding predictors of persistent depression in this population is crucial.

Purpose of the Study:

  • To prospectively analyze depression and its predictors over six months.
  • To investigate the role of negative schematic beliefs and problem-solving difficulties.

Main Methods:

  • A prospective longitudinal analysis was conducted.
  • Sixty participants with persecutory delusions were included.
  • Depression, negative schematic beliefs, and problem-solving were assessed over six months.

Main Results:

  • Negative schematic beliefs about the self predicted higher depression scores at six months.
  • Poorer problem-solving abilities also predicted higher depression scores at six months.
  • These predictions were significant beyond baseline depression levels.

Conclusions:

  • Negative schematic beliefs and problem-solving difficulties play a role in perpetuating depression in psychosis.
  • Findings support the extension of models from major depressive disorder to psychosis.
  • Further intervention research is needed to confirm causal relationships.