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Establishment of a Primary Culture of Patient-derived Soft Tissue Sarcoma
Published on: April 11, 2018
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Nodular fasciitis mimicking a soft tissue sarcoma - A case report
Vatsal Khanna1, Manikandan Rajan1, Trishya Reddy1
1Sri Ramachandra Medical College, Porur, Chennai - 600116, Tamil Nadu, India.
International Journal of Surgery Case Reports
|February 23, 2018
Summary
Nodular fasciitis, a benign tumor, was diagnosed in a 27-year-old male with a large axillary mass. Despite initial suspicion of sarcoma, histopathology confirmed nodular fasciitis, highlighting the importance of diagnostic tools.
Area of Science:
- Oncology
- Pathology
- Radiology
Background:
- Nodular fasciitis is a benign soft tissue tumor of fibroblastic/myofibroblastic differentiation.
- First described in 1955, it can present as a large mass, sometimes mimicking malignancy.
Purpose of the Study:
- To report a case of a large axillary mass initially suspected as soft tissue sarcoma.
- To emphasize the diagnostic role of histopathology and immunohistochemistry in differentiating nodular fasciitis from sarcomas.
Main Methods:
- Case report of a 27-year-old male with a 2.5-year history of right axillary swelling.
- Diagnostic imaging included Chest X-Ray, MRI, and Magnetic Resonance Angiogram.
- USG-guided biopsy followed by wide local excision and histopathological examination.
Main Results:
- A large (12x10x10.8 cm) irregular mass was identified in the right axilla.
- Imaging suggested vascular supply and drainage but no neural involvement.
- Biopsy and histopathology confirmed nodular fasciitis, ruling out soft tissue sarcoma.
Conclusions:
- Nodular fasciitis typically affects adults aged 20-40 and can present as a solitary lesion.
- Differential diagnosis includes various benign and malignant soft tissue tumors.
- Accurate diagnosis relies on histopathology and immunohistochemistry, especially for large or atypical presentations.
Keywords:
Case reportHistopathologicalMagnetic resonance angiogramMagnetic resonance imagingMuscular-subcutaneous planeNodular fasciitisMore Related Videos
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