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Development of Recombinant Proteins to Treat Chronic Pain
Published on: April 11, 2018
Development of a standardized approach for managing opioids in adults with chronic noncancer pain
Jessica M Downes1, Donald G Klepser2, Jennifer Foster2
1Department of Pharmacy Practice, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE. jessica.downes@unmc.edu.
Purpose:
The implementation of a chronic pain protocol (CPP) and its effects on the management of long-term opioid therapy are described.
Summary:
The CPP used at a federally qualified health center and primary care clinic was updated in 2015 and included a prescribing ceiling in morphine equivalent dose (MED) per day and standardized the prescribing of chronic opioids. Intermittent urine drug screening performed at least once annually was added as a requirement of the pain management contract between the provider and the patient. An electronic report was developed to identify patients who were receiving long-term opioid therapy at the clinic. The clinical pharmacists identified patients from the report whose long-term opioid doses were over the clinic-recommended MED threshold, needed a pain contract, or were due for a urine drug screen. The number of patients for whom long-term opioids were prescribed decreased for all clinicians, including an 88% reduction by nurse practitioners. Over 12 months, 97 fewer patients with chronic pain were treated with a long-term opioid at the clinic. The number of patients with pain contracts increased by 22.9% (p < 0.001), and the number of patients who had a urine drug screen over a 12-month period increased by 18.3% (p = 0.0016).
Conclusion:
The implementation of a CPP and the development of electronic reports to track provider adherence to the protocol led to a reduction in the number of chronic pain patients receiving long-term opioid therapy. The number of patients with pain contracts increased.
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