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Updated: Feb 14, 2026

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Published on: December 9, 2010
Diagnostic and therapeutic spinal interventions: Diskography
Timothy P Maus1, J D Bartleson1
1Departments of Radiology (TPM) and Neurology (JDB), Mayo Clinic, Rochester, MN.
Diskography is an invasive diagnostic test to identify internal disc disruption as a cause of axial spine pain. While useful for diagnosing discogenic pain, its role in guiding treatment is limited by a lack of validated therapies.
Area of Science:
- Spine diagnostics
- Pain management
- Interventional radiology
Background:
- Axial spine pain is often challenging to diagnose.
- Internal disc disruption is a potential cause of axial spine pain.
- Accurate diagnosis is crucial to avoid inappropriate interventions.
Purpose of the Study:
- To evaluate the diagnostic utility of diskography for axial spine pain.
- To assess the role of diskography in confirming or excluding internal disc disruption.
- To review the limitations and risks associated with diskography.
Main Methods:
- Diskography involves injecting fluid into the nucleus of the intervertebral disc under manometric control.
- A positive response is defined as reproduction of the patient's typical pain.
- Literature review to assess evidence supporting diskography in different spinal regions (lumbar, cervical, thoracic).
Main Results:
- Diskography is validated in the lumbar spine, with less support in the cervical or thoracic spine.
- Positive diskography can confirm discogenic pain and prevent interventions targeting other pain generators.
- Negative diskography can help exclude discogenic pain, preventing unnecessary disc-directed treatments.
Conclusions:
- Diskography is a valuable tool for diagnosing discogenic pain.
- The procedure has limitations, including risks of infection, neural injury, and potential accelerated disc degeneration.
- Its utility in patient selection for specific therapies is currently limited due to the lack of validated treatment options.
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