Jove
Visualize
Contact Us

Related Concept Videos

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

267
Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
267
Predicting Molecular Geometry02:27

Predicting Molecular Geometry

46.1K
VSEPR Theory for Determination of Electron Pair Geometries
46.1K
Aging01:26

Aging

833
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
833
Prediction Intervals01:03

Prediction Intervals

3.4K
The interval estimate of any variable is known as the prediction interval. It helps decide if a point estimate is dependable.
However, the point estimate is most likely not the exact value of the population parameter, but close to it. After calculating point estimates, we construct interval estimates, called confidence intervals or prediction intervals. This prediction interval comprises a range of values unlike the point estimate and is a better predictor of the observed sample value, y. 
3.4K
Drug Distribution: Volume of Distribution01:25

Drug Distribution: Volume of Distribution

7.6K
The volume of distribution refers to the theoretical volume necessary to contain the entire amount of an administered drug at the same concentration observed in the blood plasma. The body's intracellular fluid compartment, which makes up two-thirds of the total body water, is contrasted with the extracellular fluid compartment—comprising plasma and interstitial fluid—that accounts for one-third. The volume of distribution can vary depending on the characteristics of the drug.
7.6K
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

3.6K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Navigating support pathways for children with Developmental Language Disorder in Chile: caregivers' perspectives across health and education services.

Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP)·2026
Same author

You again? 14-month-olds show neural signatures of lexical-semantic activation for novel instead of familiar voices.

Brain and language·2026
Same author

Agreement Between an Artificial Intelligence-Based Meal Image Recognition System and the Weighed Dietary Record for Estimating Energy and Nutrient Intakes.

Nutrients·2026
Same author

360CityGML: Realistic and Interactive Urban Visualization System Integrating CityGML Model and 360$^{\circ }$ Videos.

IEEE transactions on visualization and computer graphics·2025
Same author

Real-time preposition comprehension in monolingual Spanish-speaking preschool children with developmental language disorder: A visual-world eye-tracking study.

Journal of communication disorders·2025
Same author

Validity of Digital Photographic Images for Dietary Assessment of Participants with Low Frequency of Home-Made Meal Intake.

Journal of nutritional science and vitaminology·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Feb 14, 2026

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

978

Gaze distribution analysis and saliency prediction across age groups.

Onkar Krishna1, Andrea Helo2,3, Pia Rämä2,4

  • 1Dept. of Information and Communication Engineering, The University of Tokyo, Tokyo, Japan.

Plos One
|February 24, 2018
PubMed
Summary

Computational models of visual attention can be improved by considering age-related differences. This study developed an age-adapted framework to predict visual saliency across diverse age groups, enhancing prediction accuracy.

More Related Videos

Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior
07:09

Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior

Published on: November 14, 2018

11.5K
Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking
13:40

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking

Published on: December 16, 2010

17.2K

Related Experiment Videos

Last Updated: Feb 14, 2026

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss
07:12

Development of a Gaze-Contingent Display Framework Designed for Perceptual and Oculomotor Research with Simulated Central Vision Loss

Published on: April 11, 2025

978
Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior
07:09

Gaze in Action: Head-mounted Eye Tracking of Children's Dynamic Visual Attention During Naturalistic Behavior

Published on: November 14, 2018

11.5K
Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking
13:40

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking

Published on: December 16, 2010

17.2K

Area of Science:

  • Computational neuroscience
  • Human-computer interaction
  • Visual perception

Background:

  • Current computational models of visual attention primarily focus on young adults.
  • Age-related variations in visual scene processing are largely overlooked.
  • Understanding these variations is crucial for developing universally applicable attention models.

Purpose of the Study:

  • To investigate age-related changes in visual scene processing.
  • To propose an age-adapted framework for computational saliency models.
  • To enhance the prediction of regions of interest across different age groups.

Main Methods:

  • Analysis of eye movement data from 82 observers across four age groups exploring visual scenes.
  • Quantification of explorativeness using saliency map entropy.
  • Utilized Area Under the Curve (AUC) metrics for agreement and center bias analysis.

Main Results:

  • Identified age-specific variations in observer explorativeness.
  • Quantified the agreement between saliency maps and fixation points across age groups.
  • Determined the influence of age on center bias tendency in visual exploration.

Conclusions:

  • The developed age-adapted saliency model demonstrates superior performance in predicting regions of interest compared to existing models.
  • The proposed framework effectively accounts for age-related differences in visual attention.
  • This research contributes to more accurate and inclusive computational models of visual attention.