[Experience with ketotifen in respiratory tract diseases]

Area of Science:

• Allergy and immunology
• Pharmacology
• Pediatric medicine

Background:

• Allergic rhinitis and bronchial asthma are common conditions.
• Effective treatments are needed for various allergen types.
• Ketotifen is an antihistamine and mast cell stabilizer.

Purpose of the Study:

• To evaluate the efficacy of ketotifen in allergic rhinitis and allergic bronchial asthma.
• To assess ketotifen's effectiveness against both inhalation and food allergens.
• To determine the safety of long-term ketotifen administration.

Main Methods:

• Two clinical studies were conducted.
• Participants with allergic rhinitis and allergic bronchial asthma were treated with ketotifen.
• Efficacy and side effects were monitored.

Main Results:

• Ketotifen demonstrated significant efficacy in treating allergic rhinitis and bronchial asthma.
• The drug was effective against common inhalation allergens (pollen, dust mites, animal hair).
• Ketotifen also showed efficacy against food allergens ingested via the gastrointestinal tract.
• Long-term administration did not reveal any toxic side effects.

Conclusions:

• Ketotifen is an effective treatment for allergic rhinitis and bronchial asthma.
• It addresses a broad range of allergens, including those from inhalation and ingestion.
• Ketotifen is safe for long-term use and can be successfully administered to children.