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Updated: Feb 14, 2026

3D Bioprinting of Murine Cortical Astrocytes for Engineering Neural-Like Tissue
Published on: July 16, 2021
Tissue and Organ 3D Bioprinting.
Zengmin Xia1, Sha Jin1, Kaiming Ye1
11 Department of Biomedical Engineering, Center of Biomanufacturing for Regenerative Medicine, Watson School of Engineering and Applied Science, Binghamton University, State University of New York (SUNY), Binghamton, NY, USA.
Three-dimensional (3D) bioprinting fabricates complex tissue constructs and living tissues. This technology advances tissue biofabrication for organ regeneration and addresses organ transplant shortages.
Area of Science:
- Biomedical Engineering
- Regenerative Medicine
- Materials Science
Background:
- Three-dimensional (3D) bioprinting creates intricate tissue constructs.
- Initially used for bone tissue engineering scaffolds.
- Now applied to living tissues like cartilage, skin, and heart valves.
Purpose of the Study:
- Review the state-of-the-art in 3D bioprinting technology.
- Discuss biomaterials utilized in 3D bioprinting.
- Update on recent advancements and applications.
Main Methods:
- Review of current literature on 3D bioprinting.
- Analysis of biomaterials and fabrication techniques.
- Exploration of applications in tissue engineering and regenerative medicine.
Main Results:
- 3D bioprinting enables heterogeneous tissue construction and complex architectures.
- Hollow channels in hydrogels are created for vascularization.
- Broad range of biomaterials are suitable for 3D bioprinting.
Conclusions:
- 3D bioprinting significantly impacts biomedical research and industry.
- Offers novel methods for industrializing tissue biofabrication.
- Holds great potential for tissue and organ regeneration, addressing transplantation needs.
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