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Use of fibers in childhood constipation treatment: systematic review with meta-analysis
Patricia Piccoli de Mello1, Diego Andre Eifer2, Elza Daniel de Mello1
1Universidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós Graduação em Saúde da Criança e do Adolescente, Porto Alegre, RS, Brazil.
Insights
Current evidence on fiber for pediatric constipation is limited. A systematic review found no significant benefits of fiber supplementation for childhood constipation, suggesting it shouldn't be routinely prescribed.
Area of Science:
- Pediatric Gastroenterology
- Nutritional Science
- Evidence-Based Medicine
Background:
- Constipation is a common issue in pediatric patients.
- Dietary fiber is often considered a primary treatment for constipation.
- Evidence on fiber supplementation efficacy in children requires synthesis.
Purpose of the Study:
- To systematically review and meta-analyze current evidence on fiber use for treating constipation in pediatric patients.
- To assess the impact of fiber intake on bowel movement frequency, stool consistency, and symptom resolution in children.
Main Methods:
- Systematic review and meta-analysis of randomized controlled trials.
- Searched major databases (PubMed, Embase, LILACS, Cochrane) up to 2016.
- Included studies on children (1-18 years) with functional constipation; analyzed outcomes like bowel movements, stool consistency, and pain.
Main Results:
- Nine studies involving 680 children were included.
- No statistically significant improvements were observed in bowel movement frequency, stool consistency, therapeutic success, fecal incontinence, or abdominal pain with fiber intake.
- High clinical heterogeneity and methodological limitations necessitate cautious interpretation of results.
Conclusions:
- A scarcity of high-quality studies limits confidence in fiber supplementation's effect on childhood constipation.
- Adequate dietary fiber intake is recommended for functional constipation.
- Fiber supplementation is not currently recommended for routine prescription in constipated children and adolescents.
Objective:
To gather current evidence on the use of fiber for constipation treatment in pediatric patients.
Source Of Data:
Systematic review with meta-analysis of studies identified through Pubmed, Embase, LILACS and Cochrane databases published up to 2016.
Inclusion Criteria:
Randomized controlled trials; patients aged between 1 and 18 years and diagnosed with functional constipation receiving or not drug treatment for constipation; articles published in Portuguese, English, Spanish, French, and German in journals accessible to the researchers.
Synthesis Of Data:
A total of 2963 articles were retrieved during the search and, after adequate evaluation, nine articles were considered relevant to the study objective. A total of 680 children were included, of whom 45% were boys. No statistical significance was observed for bowel movement frequency, stool consistency, therapeutic success, fecal incontinence, and abdominal pain with fiber intake in patients with childhood constipation. These results should be interpreted with care due to the high clinical heterogeneity between the studies and the methodological limitation of the articles selected for analysis.
Conclusions:
There is a scarcity of qualified studies to evaluate fiber supplementation in the treatment of childhood constipation, generating a low degree of confidence in estimating the real effect of this intervention on this population. Today, according to the current literature, adequate fiber intake should only be recommended for functional constipation, and fiber supplementation should not be prescribed in the diet of constipated children and adolescents.
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