Related Experiment Video
Updated: Feb 14, 2026

Detection of Histone Modifications in Plant Leaves
Published on: September 23, 2011
Two new coumarins and a new xanthone from the leaves of Rhizophora mucronata
Kaori Taniguchi1, Mariko Funasaki2, Akio Kishida1
1Institute of Biomaterials and Bioengineering, Tokyo Medicinal and Dental University, Kanda-Surugadai, Chiyoda-ku, Tokyo 101-0062, Japan.
Abstract:
Two new coumarins (1, 2) and a new xanthone (3), together with 14 known compounds-eight coumarins (4, 5, 9, 10, 12-15), three xanthones (11, 16, 17), a benzoic acid (6) and two flavonones (7, 8)-were isolated from the leaves of Rhizophora mucronata. The structures of the compounds were elucidated by spectroscopic (IR, MS, and NMR) analyses. The isolated compounds were tested for cytotoxicity against human cancer cell lines HL-60 and HeLa. Among these compounds, only compound 16 inhibited the growth of both HeLa (IC50 = 4.8 μM) and HL-60 (IC50 = 1.0 μM) cells. Compounds 4, 7, 10, and 12 exhibited moderate activity against HeLa cells (IC50 = 3.8-8.3 μM). Compounds 5, 9, 11, and 17 showed moderate activity against HL-60 cells (IC50 = 2.2-6.3 μM). Higher selectivity against HL-60 cell lines was observed for compounds 5, 9, 11, and 16 with SI values (NIH 3T3/HL-60) of 8.6, 19.2, 9.4, and 10.2, respectively.
More Related Videos
05:19A Simple Method for Imaging Arabidopsis Leaves Using Perfluorodecalin as an Infiltrative Imaging Medium
Published on: January 16, 2012
08:56Combining Analysis of DNA in a Crude Virion Extraction with the Analysis of RNA from Infected Leaves to Discover New Virus Genomes
Published on: July 27, 2018
Related Concept Videos
Leaving Groups
In general, in a nucleophilic substitution reaction, a nucleophile displaces a functional group, called the leaving group, from the substrate to give a substituted product. A leaving group departs the substrate molecule through heterolytic cleavage, taking the pair of electrons with it to become a relatively stable weak base in the form of an anion or a neutral molecule.
In a...
Basic Plant Anatomy: Roots, Stems, and Leaves
Light Acquisition
Responses to Drought and Flooding
Seed Structure and Early Development of the Sporophyte
Lung Capacity