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Updated: Feb 14, 2026

Exploring the Arginine Methylome by Nuclear Magnetic Resonance Spectroscopy
Published on: December 16, 2021
Real-time optimization of nuclear magnetic resonance experiments
Y-Q Song1, Yiqiao Tang1, M D Hürlimann1
1Schlumberger-Doll Research, Cambridge, MA 02139, USA.
Abstract:
Nuclear Magnetic Resonance (NMR) experiments are typically performed with predetermined pulse sequences and acquisition parameters, and are oftentimes sub-optimal for individual samples under investigation. Here we explore a class of real-time optimization methods that conducts stochastic analyses on the acquired data and in turn updates and optimizes the subsequent measurements. We show superiority of the method to static approaches, both in the efficiency and quality of data acquisition, for a wide range of experiments.
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