Related Experiment Video
Updated: Feb 14, 2026

Analyzing Neural Activity and Connectivity Using Intracranial EEG Data with SPM Software
Published on: October 30, 2018
RPPAware: A software suite to preprocess, analyze and visualize reverse phase protein array data
A Ranjitha Dhanasekaran1,2,3, Katheleen J Gardiner3,4,5
1* Rocky Mountain Alzheimer's Disease Center, School of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado 80045, USA.
Abstract:
Reverse Phase Protein Arrays (RPPA) is a high-throughput technology used to profile levels of protein expression. Handling the large datasets generated by RPPA can be facilitated by appropriate software tools. Here, we describe RPPAware, a free and intuitive software suite that was developed specifically for analysis and visualization of RPPA data. RPPAware is a portable tool that requires no installation and was built using Java. Many modules of the tool invoke R to utilize the statistical features. To demonstrate the utility of RPPAware, data generated from screening brain regions of a mouse model of Down syndrome with 62 antibodies were used as a case study. The ease of use and efficiency of RPPAware can accelerate data analysis to facilitate biological discovery. RPPAware 1.0 is freely available under GNU General Public License from the project website at http://downsyndrome.ucdenver.edu/iddrc/rppaware/home.htm along with a full documentation of the tool.
More Related Videos
12:22The Use of Reverse Phase Protein Arrays RPPA to Explore Protein Expression Variation within Individual Renal Cell Cancers
Published on: January 22, 2013
15:25Tomato Analyzer: A Useful Software Application to Collect Accurate and Detailed Morphological and Colorimetric Data from Two-dimensional Objects
Published on: March 16, 2010
Related Concept Videos
Statistical Software for Data Analysis and Clinical Trials
GIS Software, Hardware, and Sources of GIS Data
Statistical Methods for Analyzing Epidemiological Data
Statistical Methods to Analyze Parametric Data: ANOVA
One-way ANOVA is applied when a single independent variable or factor is scrutinized. It compares...
Statistical Methods to Analyze Parametric Data: Student t-Test and Goodness-of-Fit Test
The Student's t-test is a statistical test that examines if there is a statistically significant difference between the means of two groups. This test is instrumental when dealing with...
Phase Transitions: Sublimation and Deposition