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Haemoplasmosis in cats: European guidelines from the ABCD on prevention and management
Insights
Haemotropic bacteria called haemoplasmas can cause anemia in cats. While Mycoplasma haemofelis is most pathogenic, other species can affect immunocompromised cats, with PCR being the preferred diagnostic method.
Area of Science:
- Veterinary Medicine
- Microbiology
- Infectious Diseases
Background:
- Haemoplasmas are haemotropic bacteria causing anemia in mammals.
- Three main feline haemoplasma species exist: Mycoplasma haemofelis, 'Candidatus Mycoplasma haemominutum', and 'Candidatus Mycoplasma turicensis'.
- Infection can be asymptomatic, but Mycoplasma haemofelis is highly pathogenic, while the other two species may affect immunocompromised cats.
Purpose of the Study:
- To summarize current knowledge on feline haemoplasma infections.
- To outline diagnostic and treatment strategies for haemoplasma infections in cats.
Main Methods:
- Review of existing literature on feline haemoplasma.
- Discussion of diagnostic techniques and treatment protocols.
Main Results:
- Mycoplasma haemofelis is the most virulent feline haemoplasma species.
- 'Candidatus M. haemominutum' and 'Candidatus M. turicensis' are less pathogenic but can cause disease in immunocompromised cats.
- PCR assays are the preferred diagnostic method; doxycycline is often effective for Mycoplasma haemofelis, though complete clearance is not guaranteed.
Conclusions:
- Feline haemoplasma infections are diverse, with varying pathogenicity.
- Effective diagnosis relies on PCR, and treatment requires careful consideration of the specific species involved.
- Further research is needed on the antibiotic responsiveness of 'Candidatus M. haemominutum' and 'Candidatus M. turicensis'.
Overview:
Haemoplasmas are haemotropic bacteria that can induce anaemia in a wide range of mammalian species. Infection in cats: Mycoplasma haemofelis is the most pathogenic of the three main feline haemoplasma species known to infect cats. ' Candidatus Mycoplasma haemominutum' and ' Candidatus Mycoplasma turicensis' are less pathogenic but can result in disease in immunocompromised cats. Male, non-pedigree cats with outdoor access are more likely to be haemoplasma infected, and ' Candidatus M haemominutum' is more common in older cats. All three haemoplasma species can be carried asymptomatically. Transmission: The natural mode of transmission of haemoplasma infection is not known, but aggressive interactions and vectors are possibilities. Transmission by blood transfusion can occur and all blood donors should be screened for haemoplasma infection.
Diagnosis And Treatment:
PCR assays are the preferred diagnostic method for haemoplasma infections. Treatment with doxycycline for 2-4 weeks is usually effective for M haemofelis-associated clinical disease (but this may not clear infection). Little information is currently available on the antibiotic responsiveness of ' Candidatus M haemominutum' and ' Candidatus M turicensis'.
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