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Updated: Feb 14, 2026

Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
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Polyneuropathies.

Claudia Sommer1, Christian Geber, Peter Young

  • 1Department of Neurology, University Hospital Würzburg; DRK Pain Center Mainz; Department of Sleep Medicine and Neuromuscular Disorders, Münster University; University Orthopedic Clinic Erlangen; Department of Neurology, University Hospital Mainz; Friedrich-Baur Institute, Department of Neurology, Ludwig-Maximilians-Universität Munich.

Deutsches Arzteblatt International
|February 27, 2018
PubMed
Summary
This summary is machine-generated.

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Peripheral neuropathies are common in older adults. Identifying the cause is crucial for effective treatment, with diabetes and chemotherapy being significant contributors. Early diagnosis and specialized evaluation improve patient outcomes.

Area of Science:

  • Neurology
  • Peripheral Nervous System Disorders

Background:

  • Peripheral neuropathies are common, affecting 5-8% of adults, particularly the elderly.
  • Treatment efficacy hinges on precise etiological identification through diagnostic evaluation.

Purpose of the Study:

  • To review current guidelines and evidence on non-hereditary polyneuropathies.
  • To emphasize the importance of timely diagnosis for effective treatment.

Main Methods:

  • Literature review of guidelines, cohort studies, and randomized controlled trials (2000-2017).
  • Selective PubMed search focusing on non-hereditary polyneuropathies.

Main Results:

  • Diabetes is the leading cause in Europe/North America; alcohol-associated neuropathy affects 22-66% of chronic alcoholics.

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  • Chemotherapy-induced neuropathies (CIN) are increasingly important (30-40% prevalence).
  • Other causes include genetic factors, vitamin deficiencies, toxins, and immunological processes. Pain is common and treatable; exercise and physiotherapy can help.

    • Conclusions:

    • Timely diagnosis of polyneuropathy cause is essential for specific treatment.
    • Severe cases with unidentified causes warrant referral to specialized centers for comprehensive evaluation.