Gaps in Knowledge About the Association Between Maternal Periodontitis and Adverse Obstetric Outcomes: An Umbrella

Annie M Vivares-Builes1, Leidy Johana Rangel-Rincón1, Javier Enrique Botero1

  • 1Faculty of Dentistry, Universidad de Antioquia, Medellín, Colombia.

Insights

Maternal periodontitis is linked to adverse pregnancy outcomes like low birth weight, preterm delivery, and preeclampsia. Further research is needed to address gaps in understanding this association.

Area of Science:

  • Reproductive Health
  • Periodontology
  • Maternal-Fetal Medicine

Background:

  • Periodontal disease during pregnancy is linked to obstetric and neonatal complications.
  • These complications can impact childhood development and adult cardiovascular health.

Purpose of the Study:

  • To summarize evidence on the association between maternal periodontitis and obstetric complications.
  • To identify research gaps concerning maternal periodontitis and pregnancy outcomes.

Main Methods:

  • Umbrella review of systematic reviews and meta-analyses.
  • Quality evaluation and descriptive analysis of included studies.

Main Results:

  • Nineteen systematic reviews comprising 99 observational studies were analyzed.
  • Most reviews found an association between maternal periodontitis and increased risk of low birth weight, preterm delivery, and preeclampsia.
  • The strength and significance of this association vary based on study context.

Conclusions:

  • Established association between maternal periodontitis and adverse pregnancy outcomes.
  • Identified conceptual and methodological gaps require consideration in future research.
Abstract

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