Related Experiment Video
Updated: Feb 14, 2026

07:58
Bio-inspired Polydopamine Surface Modification of Nanodiamonds and Its Reduction of Silver Nanoparticles
Published on: November 14, 2018
8.8K
Silver Diamine Fluoride Arrests Caries in Primary Teeth
The Journal of Evidence-Based Dental Practice
|February 27, 2018
Summary
Silver Diamine Fluoride (SDF) effectively controls the progression of cavities in primary teeth. This systematic review and meta-analysis confirms SDF as a valuable tool for managing early childhood caries.
Area of Science:
- Dentistry
- Cariology
- Public Health
Background:
- Early childhood caries (ECC) poses a significant global oral health challenge.
- Effective management strategies are crucial for preserving primary dentition.
- Silver Diamine Fluoride (SDF) has emerged as a promising minimally invasive treatment option.
Purpose of the Study:
- To systematically review and meta-analyze the efficacy of Silver Diamine Fluoride (SDF) in controlling caries progression in primary teeth.
- To evaluate the available scientific evidence on SDF's effectiveness in arresting dentinal caries lesions.
Main Methods:
- A comprehensive systematic literature search was conducted across multiple databases.
- Studies meeting predefined inclusion criteria were selected for meta-analysis.
- Data on caries arrest and progression rates following SDF application were extracted and analyzed.
Main Results:
- The meta-analysis demonstrated a statistically significant higher rate of caries arrest in primary teeth treated with SDF compared to control groups.
- SDF application was found to be effective in arresting dentinal caries progression.
- No significant adverse events were reported in the included studies.
Conclusions:
- Silver Diamine Fluoride (SDF) is a highly effective and safe intervention for controlling caries progression in primary teeth.
- SDF represents a valuable, minimally invasive therapeutic option for managing early childhood caries.
- Further research should focus on long-term outcomes and optimal application protocols.
Related Concept Videos
Teeth
1.8K
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
1.8K
Primary Active Transport
201.0K
In contrast to passive transport, active transport involves a substance being moved through membranes in a direction against its concentration or electrochemical gradient. There are two types of active transport: primary active transport and secondary active transport. Primary active transport utilizes chemical energy from ATP to drive protein pumps that are embedded in the cell membrane. With energy from ATP, the pumps transport ions against their electrochemical gradients—a direction...
201.0K
Primary Active Transport
14.5K
In contrast to passive transport, active transport involves a substance being moved through membranes in a direction against its concentration or electrochemical gradient. There are two types of active transport: primary active transport and secondary active transport. Primary active transport utilizes chemical energy from ATP to drive protein pumps embedded in the cell membrane. With energy from ATP, the pumps transport ions against their electrochemical gradients—a direction they would...
14.5K
Primary and Secondary Growth in Roots and Shoots
60.7K
Vascular plants, which account for over 90% of the Earth’s vegetation, all undergo primary growth—which lengthens roots and shoots. Many land plants, notably woody plants, also undergo secondary growth—which thickens roots and shoots.
60.7K
Primary Production
25.5K
The total amount of energy acquired by primary producers in an ecosystem is called gross primary production (GPP). However, of this energy, producers use some for metabolic processes, and some is lost as heat, decreasing the amount of energy available to the next trophic level. The remaining usable amount of energy is called the net primary productivity (NPP). In terrestrial ecosystems, NPP is driven by climate, while light penetration and nutrient availability drive NPP in aquatic ecosystems.
25.5K
Primary Distribution
556
Primary distribution systems deliver electrical power from substations to consumers through various voltage classes, with 15-kV class voltages being predominant among U.S. utilities. Older 2.5- and 5-kV classes are being replaced by 15-kV primaries, while higher 25- to 34.5-kV classes are used in high-density urban areas and rural regions with long feeders. Three-phase, four-wire multigrounded systems are widely employed for balanced power delivery, using the neutral wire as a grounding point.
556

