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Memorcise and Alzheimer's disease
Paul D Loprinzi1, Emily Frith1, Pamela Ponce1
1a Physical Activity Epidemiology Laboratory, Exercise Psychology Laboratory, Department of Health, Exercise Science and Recreation Management , The University of Mississippi , University , MS , USA.
The Physician and Sportsmedicine
|February 27, 2018
Summary
Regular exercise may improve memory in Alzheimer's disease (AD) patients. This review explores how physical activity impacts AD mechanisms, prevention, and memory, offering guidance for clinicians.
Area of Science:
- Neuroscience
- Gerontology
- Exercise Science
Background:
- Alzheimer's disease (AD) is a neurodegenerative disorder significantly impacting memory and cognitive functions.
- Current therapeutic strategies for AD have limitations, necessitating exploration of complementary interventions.
Purpose of the Study:
- To review the scientific literature on the relationship between exercise and Alzheimer's disease.
- To elucidate the mechanisms by which exercise may prevent AD and mitigate its progression.
- To examine the effects of exercise on memory in individuals with existing AD and provide recommendations.
Main Methods:
- This study is a narrative review of existing research.
- It synthesizes findings on AD pathophysiology, exercise's role in prevention and treatment, and its impact on memory.
Main Results:
- Exercise shows potential in preventing AD and slowing disease progression.
- Physical activity is associated with improved memory function in individuals with AD.
- Mechanisms include neuroprotection, reduced neuroinflammation, and enhanced neurogenesis.
Conclusions:
- Exercise is a promising behavioral strategy for both preventing and managing Alzheimer's disease.
- Clinicians can utilize exercise interventions to support cognitive health in AD patients.
- Further research into 'memorcise' can optimize therapeutic approaches.