Compatibility of enflurane and adrenaline--experiments in the dog

Anaesthetised, intubated dogs were ventilated with 1, 2, 3, 4 and 5% enflurane and received adrenaline, 1.4 microgram/kg/min, by intravenous infusion for 5 min. No further adrenaline was given if cardiac arrhythmias occurred. Depth of anaesthesia was controlled by measurement of enflurane levels in arterial blood by an original method. No relationship was observed between the inspired enflurane concentrations and the onset of cardiac arrhythmias.