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Physical Activity in Early Parkinson Disease
Sneha Mantri1,2, Michelle E Fullard1,2, John E Duda1,2
1Parkinson's Disease Research, Education, and Clinical Center, Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.
Physical activity is crucial for Parkinson disease (PD) management. Early PD patients and healthy controls reported low activity levels, underscoring the need for increased exercise promotion.
Area of Science:
- Neurology
- Movement Disorders
- Exercise Science
Background:
- Physical activity and exercise are known to improve outcomes in Parkinson disease (PD).
- Limited data exists regarding physical activity levels in individuals diagnosed with early-stage PD.
Purpose of the Study:
- To assess self-reported physical activity levels in early Parkinson disease patients.
- To investigate associations between activity scores and clinical characteristics in PD subjects compared to healthy controls.
Main Methods:
- Utilized self-reported activity scores from 383 PD subjects and 175 healthy controls.
- Data sourced from the Parkinson Progression Markers Initiative (PPMI) database.
- Analyzed associations between activity scores and demographic/clinical factors.
Main Results:
- PD subjects reported 8% lower activity scores than healthy controls (162.6±86.2 vs 175.0±78.5, p=0.10).
- Higher activity scores correlated with younger age and male sex.
- A significant proportion of both PD subjects (47%) and healthy controls (44%) did not meet recommended physical activity guidelines.
Conclusions:
- Physical activity levels are suboptimal in early Parkinson disease.
- Exercise interventions should be encouraged early in the PD trajectory.
- Findings emphasize the importance of promoting physical activity for all adults, including those with early PD.
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