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Pressure dependent release of atrial natriuretic peptide (ANP) in patients with chronic cardiac diseases: does it
Abstract:
In patients with chronic cardiac disease plasma concentrations of atrial natriuretic peptide are elevated. The close relationships obtained between right (and/or left) atrial pressure and the peptide concentrations suggest a non-resetting phenomenon of the pressure induced release mechanism in the presence of a maintained responsiveness to acute stimuli.