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Trabecular Meshwork Response to Pressure Elevation in the Living Human Eye
Published on: June 20, 2015
Acute blood pressure elevation: Therapeutic approach
Massimo Salvetti1, Anna Paini1, Fabio Bertacchini1
1Department of Clinical and Experimental Sciences University of Brescia, 2a medicina Spedali Civili, Brescia, 25100, Italy.
Insights
International guidelines recommend distinguishing between hypertensive emergencies and urgencies, not using "hypertensive crisis." Hypertensive emergencies remain a significant cause of mortality, necessitating updated treatment strategies.
Area of Science:
- Cardiology
- Nephrology
- Internal Medicine
Background:
- International guidelines suggest avoiding the term "hypertensive crisis."
- Hypertensive emergencies and urgencies are distinct clinical presentations with different management approaches.
- Despite increased hypertension awareness, control, and treatment, hypertensive emergencies persist with high mortality.
Purpose of the Study:
- To provide an updated review of current data on the treatment of hypertensive emergencies.
- To clarify the diagnostic and therapeutic distinctions between hypertensive emergencies and urgencies.
- To highlight suboptimal adherence to international guidelines in managing hypertensive emergencies.
Main Methods:
- Literature review of recent studies on hypertensive emergencies.
- Analysis of international guidelines and clinical recommendations.
- Synthesis of data on diagnostic criteria and therapeutic interventions.
Main Results:
- Hypertensive emergencies are characterized by severely elevated blood pressure with evidence of acute target organ damage.
- Treatment of hypertensive emergencies requires prompt BP reduction to prevent further organ damage.
- Adherence to guideline-recommended treatment targets and drug choices in hypertensive emergencies is often suboptimal.
Conclusions:
- Accurate classification of severe hypertension into emergencies or urgencies is crucial for appropriate management.
- Effective treatment of hypertensive emergencies can mitigate mortality and morbidity.
- Further efforts are needed to improve adherence to evidence-based guidelines for hypertensive emergencies.
Abstract:
International guidelines have suggested to avoid the term "hypertensive crisis" for the description of an acute and severe increase in blood pressure (BP) and to consider the definition of 'hypertensive emergencies' or 'hypertensive urgencies'. These two clinical presentations are characterized by the presence of high BP values but imply a different diagnostic and therapeutic approach. Hypertension awareness, treatment and control are slightly increased in the last years mostly in the United States and in some European nations. Nevertheless the prevalence of hypertensive emergencies is still high and remains associated to a higher mortality. International Guidelines have also given some recommendations regarding the target BP during treatment and the use of antihypertensive drugs in hypertensive emergencies, although the adherence to these indications is frequently suboptimal. The present paper is aimed to update the currently available data on the treatment of hypertensive emergencies.
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