Acute blood pressure elevation: Therapeutic approach

Massimo Salvetti1, Anna Paini1, Fabio Bertacchini1

  • 1Department of Clinical and Experimental Sciences University of Brescia, 2a medicina Spedali Civili, Brescia, 25100, Italy.

Pharmacological Research
|February 27, 2018
PubMed

Insights

International guidelines recommend distinguishing between hypertensive emergencies and urgencies, not using "hypertensive crisis." Hypertensive emergencies remain a significant cause of mortality, necessitating updated treatment strategies.

Area of Science:

  • Cardiology
  • Nephrology
  • Internal Medicine

Background:

  • International guidelines suggest avoiding the term "hypertensive crisis."
  • Hypertensive emergencies and urgencies are distinct clinical presentations with different management approaches.
  • Despite increased hypertension awareness, control, and treatment, hypertensive emergencies persist with high mortality.

Purpose of the Study:

  • To provide an updated review of current data on the treatment of hypertensive emergencies.
  • To clarify the diagnostic and therapeutic distinctions between hypertensive emergencies and urgencies.
  • To highlight suboptimal adherence to international guidelines in managing hypertensive emergencies.

Main Methods:

  • Literature review of recent studies on hypertensive emergencies.
  • Analysis of international guidelines and clinical recommendations.
  • Synthesis of data on diagnostic criteria and therapeutic interventions.

Main Results:

  • Hypertensive emergencies are characterized by severely elevated blood pressure with evidence of acute target organ damage.
  • Treatment of hypertensive emergencies requires prompt BP reduction to prevent further organ damage.
  • Adherence to guideline-recommended treatment targets and drug choices in hypertensive emergencies is often suboptimal.

Conclusions:

  • Accurate classification of severe hypertension into emergencies or urgencies is crucial for appropriate management.
  • Effective treatment of hypertensive emergencies can mitigate mortality and morbidity.
  • Further efforts are needed to improve adherence to evidence-based guidelines for hypertensive emergencies.

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