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Updated: Feb 14, 2026
Layer Microdissection of Tricuspid Valve Leaflets for Biaxial Mechanical Characterization and Microstructural Quantification
Published on: February 10, 2022
Radiopathologic correlation of a tricuspid valve papillary fibroelastoma detected in an infant
Maddy Artunduaga1, Siddharth P Jadhav1, Karen W Eldin2
1Department of Radiology, Texas Children's Hospital, Baylor College of Medicine, 6701 Fannin Street Suite 470, Houston, TX 77030.
Insights
Papillary fibroelastomas, rare pediatric heart tumors, can occur on the tricuspid valve. Cardiac MRI effectively diagnosed this rare tumor in an infant, distinguishing it from a thrombus.
Area of Science:
- Cardiology
- Pediatric Oncology
- Diagnostic Imaging
Background:
- Papillary fibroelastomas are rare, benign primary cardiac tumors.
- They typically arise from heart valves but are uncommon in children.
- Tricuspid valve involvement is exceptionally rare, with limited pediatric cases reported.
Observation:
- An 11-month-old infant presented with a heart murmur detected since birth.
- Cardiac magnetic resonance imaging (CMR) was utilized for diagnostic evaluation.
- The imaging aimed to differentiate a potential cardiac mass from a thrombus.
Findings:
- A papillary fibroelastoma originating from the tricuspid valve was identified.
- This represents a rare instance of this tumor type in an infant.
- CMR provided crucial characterization of the cardiac mass.
Implications:
- This case highlights the utility of cardiac MRI in diagnosing rare pediatric cardiac tumors.
- It expands the understanding of papillary fibroelastoma presentation in infants.
- Early and accurate diagnosis is vital for appropriate management of pediatric cardiac masses.
Abstract:
Papillary fibroelastomas are benign primary cardiac tumors that usually arise from the valve apparatus and are rare in the pediatric population. Involvement of the tricuspid valve is even less common with only a few cases reported in the literature. Cardiac magnetic resonance imaging is a valuable examination that aids in differentiating a tumor from a thrombus. We present the case of an 11-month-old girl referred by her pediatrician to investigate a murmur noted since birth. To our knowledge, this is the first report of a pathologically proven papillary fibroelastoma arising from the tricuspid valve characterized by magnetic resonance imaging in an infant.
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