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Published on: June 7, 2015
Myxoid-round cell liposarcoma: MRI appearance after radiation therapy and relationship to response
Michael Rosenberg1, John V Groth2, Mihra S Taljanovic3
1Department of Radiology, University of Illinois Hospital & Health Sciences System, 1740 West Taylor Street, Suite 2600, Chicago, IL 60612.
Abstract:
Liposarcomas are classified into 4 different subtypes, with the myxoid-round cell variant demonstrating increased morbidity and metastatic potential dependent on cell composition. Unique to sarcomas, the myxoid-round cell liposarcoma is remarkably sensitive to radiation therapy in the pretreatment setting, owing to the tumor morphology and vascular distribution. Herein we report a case of myxoid-round cell liposarcoma within the deep soft tissues of the thigh of an 81-year-old male with excellent neoadjuvant response to radiation. We briefly review treatment options.
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