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Updated: Feb 13, 2026

Predicting Treatment Response to Image-Guided Therapies Using Machine Learning: An Example for Trans-Arterial Treatment of Hepatocellular Carcinoma

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Factors Predicting a Good Symptomatic Outcome After Prostate Artery Embolisation (PAE).

D Maclean¹, M Harris², T Drake²

¹Department of Radiology, University Hospital Southampton, Southampton, UK. dfwmaclean@doctors.org.uk.

Cardiovascular and Interventional Radiology

|February 28, 2018

Summary

Prostate artery embolisation (PAE) success for benign prostatic obstruction depends on initial prostate size and 3-month volume reduction. These factors help predict good symptomatic outcomes at 12 months, aiding patient selection and counseling.

Keywords:

BPH Embolization Outcome PAE Predictor Prostate

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Area of Science:

Urology
Interventional Radiology

Background:

Prostate artery embolisation (PAE) is an established treatment for benign prostatic obstruction.
Predictors of successful symptomatic outcome following PAE remain unclear.
The role of pre-embolisation prostate size is controversial.

Purpose of the Study:

To investigate the association between prostate size and clinical benefit after PAE.
To evaluate percentage prostate volume reduction as a predictor of symptomatic outcome post-PAE.

Main Methods:

Prospective follow-up of 86 PAE patients.
Analysis of clinical improvement using International Prostate Symptom Score (IPSS).
Multiple linear regression and Pearson's bivariate analysis to assess variable associations.

Main Results:

72.1% of patients achieved clinical success at 12 months.
Initial prostate size and percentage volume reduction showed significant association with clinical improvement.
Percentage volume reduction at 3 months had the strongest correlation (r=0.68, p<0.001) with 12-month symptomatic improvement.

Conclusions:

Both initial prostate size and 3-month percentage volume reduction predict good 12-month symptomatic outcomes.
These findings assist in patient selection and counseling for optimal PAE results.