Factors Predicting a Good Symptomatic Outcome After Prostate Artery Embolisation (PAE)
D Maclean1, M Harris2, T Drake2
1Department of Radiology, University Hospital Southampton, Southampton, UK. dfwmaclean@doctors.org.uk.
Cardiovascular and Interventional Radiology
|February 28, 2018
Summary
Prostate artery embolisation (PAE) success for benign prostatic obstruction depends on initial prostate size and 3-month volume reduction. These factors help predict good symptomatic outcomes at 12 months, aiding patient selection and counseling.
Area of Science:
- Urology
- Interventional Radiology
Background:
- Prostate artery embolisation (PAE) is an established treatment for benign prostatic obstruction.
- Predictors of successful symptomatic outcome following PAE remain unclear.
- The role of pre-embolisation prostate size is controversial.
Purpose of the Study:
- To investigate the association between prostate size and clinical benefit after PAE.
- To evaluate percentage prostate volume reduction as a predictor of symptomatic outcome post-PAE.
Main Methods:
- Prospective follow-up of 86 PAE patients.
- Analysis of clinical improvement using International Prostate Symptom Score (IPSS).
- Multiple linear regression and Pearson's bivariate analysis to assess variable associations.
Main Results:
- 72.1% of patients achieved clinical success at 12 months.
- Initial prostate size and percentage volume reduction showed significant association with clinical improvement.
- Percentage volume reduction at 3 months had the strongest correlation (r=0.68, p<0.001) with 12-month symptomatic improvement.
Conclusions:
- Both initial prostate size and 3-month percentage volume reduction predict good 12-month symptomatic outcomes.
- These findings assist in patient selection and counseling for optimal PAE results.
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