Related Experiment Video
Updated: Feb 13, 2026

Single-Molecule Diffusion and Assembly on Polymer-Crowded Lipid Membranes
Published on: July 19, 2022
Preparation and Properties of Asymmetric Synthetic Membranes Based on Lipid and Polymer Self-Assembly
Ariane Peyret1, Hang Zhao1, Sébastien Lecommandoux1
1Laboratoire de Chimie des Polymères Organiques, LCPO, Université de Bordeaux, CNRS, Bordeaux INP, UMR 5629 , 16 Avenue Pey Berland F-33600 Pessac , France.
Abstract:
Cell membrane asymmetry is a common structural feature of all biological cells. Researchers have tried for decades to better study its formation and its function in membrane-regulated phenomena. In particular, there has been increasing interest in developing synthetic asymmetric membrane models in the laboratory, with the aim of studying basic physical chemistry properties that may be correlated to a relevant biological function. The present article aims to summarize the main presented approaches to prepare asymmetric membranes, which are most often made from lipids, polymers, or a combination of both.
Related Concept Videos
Asymmetric Lipid Bilayer
Polymers
Assembly of the Lipid Bilayer in the ER
A large chunk of any biological membrane is composed of phospholipids. These lipids have a heterogeneous distribution across different subcellular organelles and even between...
Membrane Lipids
Phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, and sphingomyelin are the most common phospholipids present in mammalian membranes. At physiological pH, phosphatidylserine is negatively charged, while the other three...
What are Lipids?
Structure of Lipids

