Complete Lower Extremity Revascularization via a Hybrid Procedure for Patients with Critical Limb Ischemia

Toshio Takayama1, Jon S Matsumura1

  • 11 Division of Vascular Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

Insights

Complete revascularization using hybrid procedures significantly improved limb salvage for critical limb ischemia (CLI) patients. This approach reduced major amputation rates and enhanced amputation-free survival, demonstrating its benefit in treating CLI.

Area of Science:

  • Vascular Surgery
  • Interventional Cardiology
  • Endovascular Therapy

Background:

  • Complete revascularization (CR) is crucial for treating critical limb ischemia (CLI).
  • Hybrid procedures, combining endarterectomy and endovascular treatment, are common for complex lower extremity lesions.
  • This study evaluates the efficacy of CR via hybrid procedures for limb salvage in CLI patients.

Purpose of the Study:

  • To investigate the effectiveness of complete revascularization achieved by hybrid procedures in limb salvage for patients with critical limb ischemia (CLI).

Main Methods:

  • A retrospective analysis of 61 CLI patients (95 limbs) treated with lower extremity hybrid procedures between 2010 and 2016.
  • Patients were categorized into complete revascularization (CR, n=37) and incomplete revascularization (IR, n=24) groups.
  • Key outcomes analyzed included postoperative ankle-brachial index (ABI), patency rates, and major amputation rates.

Main Results:

  • The CR group showed significantly higher postoperative ABIs (0.87 vs. 0.53) and a trend towards lower major amputation rates (2.7% vs. 13%).
  • Major amputation-free survival at 3 years was higher in the CR group (97% vs. 81%).
  • Despite higher initial limb ischemia severity (Rutherford 5) in the CR group, outcomes were favorable.

Conclusions:

  • Complete lower extremity revascularization achieved through hybrid procedures is beneficial for critical limb ischemia (CLI) patients.
  • This approach effectively reduces major amputation rates and improves limb salvage.
  • Hybrid procedures offer a viable strategy for achieving CR and improving outcomes in CLI.
Abstract

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