Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Stroke Volume01:27

Regulation of Stroke Volume

5.2K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
5.2K
Cardiac Output and Stroke Volume01:11

Cardiac Output and Stroke Volume

4.9K
Cardiac output (CO) is an integral aspect of human physiology, reflecting the heart's efficiency and responsiveness to the body's needs. It represents the volume of blood that the left or right ventricle ejects into the aorta or pulmonary trunk each minute. The CO is calculated by multiplying the heart rate (HR)—the number of heartbeats per minute—by the stroke volume (SV)—the amount of blood pumped out with each heartbeat.
In an average resting adult male, the typical cardiac...
4.9K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.0K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.0K
Treatment Resistant Cancers02:56

Treatment Resistant Cancers

3.8K
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
3.8K
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

1.2K
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
1.2K
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

981
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
981

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Early versus Late starting of Direct Oral Anticoagulants after breakthrough ischemic stroke: A Target Trial Analysis from the ASPERA-R Study.

International journal of stroke : official journal of the International Stroke Society·2026
Same author

An international, multispecialty consensus document on the optimal management of patients with internal carotid artery occlusion.

Journal of vascular surgery·2026
Same author

The Interplay Between Immunometabolism and Neuroinflammation in Alzheimer's Disease.

Biomolecules·2026
Same author

Continuation vs Switching Direct Oral Anticoagulant Therapy After Breakthrough Stroke.

JAMA network open·2026
Same author

Botulinum Toxin for Chronic Migraine: Beyond Headache Reduction and Toward Possible Cognitive Benefits.

Toxins·2026
Same author

Competing Stroke Etiologies and Outcomes After Breakthrough Ischemic Stroke on Oral Anticoagulants in Patients With Atrial Fibrillation.

Neurology·2026

Related Experiment Video

Updated: Feb 13, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.7K

Future challenges of stroke treatment.

Simona Lattanzi1, Mauro Silvestrini1

  • 1Neurological Clinic, Department of Experimental and Clinical Medicine, Marche Polytechnic University, Ancona, Italy.

Neurologia I Neurochirurgia Polska
|March 1, 2018
PubMed
Summary

Acute basilar artery occlusion (BAO), a severe stroke type, has poor outcomes and unestablished optimal management. Mechanical thrombectomy

Area of Science:

  • Neurology
  • Vascular Neurology
  • Stroke Medicine

Background:

  • Posterior circulation stroke comprises 20% of ischemic strokes.
  • Acute basilar artery occlusion (BAO) is a critical subtype with high mortality and disability rates.
  • Current BAO management relies on consensus, leading to variable clinical practices.

Discussion:

  • The efficacy of mechanical thrombectomy for BAO requires further robust estimation.
  • Optimal treatment strategies for BAO remain undetermined.
  • Significant advancements in stroke care have been made, yet critical questions persist.

Key Insights:

  • BAO presents a severe clinical challenge with limited established treatment protocols.
  • Mechanical thrombectomy's precise benefit in BAO is yet to be fully quantified.
Keywords:
Basilar artery occlusionStrokeThrombectomyThrombolysis

More Related Videos

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice
06:54

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

Published on: June 22, 2022

3.3K
Using Generative Art to Convey Past and Future Climate Transitions
06:10

Using Generative Art to Convey Past and Future Climate Transitions

Published on: March 31, 2023

1.5K

Related Experiment Videos

Last Updated: Feb 13, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

12.7K
A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice
06:54

A Model for Encephalomyosynangiosis Treatment after Middle Cerebral Artery Occlusion-Induced Stroke in Mice

Published on: June 22, 2022

3.3K
Using Generative Art to Convey Past and Future Climate Transitions
06:10

Using Generative Art to Convey Past and Future Climate Transitions

Published on: March 31, 2023

1.5K
  • Existing treatment approaches are largely consensus-driven and lack definitive evidence.

    • Outlook:

    • Future research should focus on establishing evidence-based guidelines for BAO management.
    • Further investigation into the role and effectiveness of mechanical thrombectomy is crucial.
    • Addressing unanswered questions in BAO treatment will drive future advancements in stroke care.