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Continuous Fluorescence-Based Endonuclease-Coupled DNA Methylation Assay to Screen for DNA Methyltransferase Inhibitors
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Bicyclo((aryl)methyl)benzamides as inhibitors of GlyT1

Jeffrey G Varnes1, Hui Xiong1, Janet M Forst1

  • 1Medicinal Chemistry, Neuroscience, IMED Biotech Unit, AstraZeneca, Wilmington, DE, USA.

Bioorganic & Medicinal Chemistry Letters
|March 1, 2018
PubMed

Keywords:
GlyT1Glycine uptake inhibitionN-Methyl-d-aspartate receptorNMDArSchizophrenia

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