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Updated: Feb 13, 2026

Author Spotlight: Analyzing Bone Marrow Microenvironment in Murine Hematological Malignancies
Published on: November 10, 2023
The interplay of leukemia cells and the bone marrow microenvironment
Delfim Duarte1,2, Edwin D Hawkins3,4, Cristina Lo Celso1,2
1Department of Life Sciences, Imperial College London, London, United Kingdom.
None:
The interplay of cancer cells and surrounding stroma is critical in disease progression. This is particularly evident in hematological malignancies that infiltrate the bone marrow and peripheral lymphoid organs. Despite clear evidence for the existence of these interactions, the precise repercussions on the growth of leukemic cells are poorly understood. Recent development of novel imaging technology and preclinical disease models has advanced our comprehension of leukemia-microenvironment crosstalk and has potential implications for development of novel treatment options.
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