Related Experiment Video
Updated: Feb 13, 2026

The WATCHMAN Left Atrial Appendage Closure Device for Atrial Fibrillation
Published on: February 28, 2012
Beating-heart Thoracoscopic Left Atrial Appendage Exclusion in a Patient with Left atrial Thrombus
1Professor of Cardiovascular Surgery Cedars-Sinai Medical Center, Los Angeles, CA.
Insights
For patients with atrial fibrillation and contraindications to anticoagulation, left atrial appendage exclusion offers a stroke risk reduction strategy. This case study highlights a novel device for managing these challenging clinical scenarios.
Area of Science:
- Cardiology
- Medical Devices
- Thrombosis Management
Background:
- Atrial fibrillation is a leading cause of stroke and death.
- Anticoagulation is standard but not suitable for all patients.
- Managing anticoagulation-intolerant patients with atrial fibrillation poses a clinical challenge.
Abstract:
Stroke remains a major complication of atrial fibrillation and third leading cause of death in Western Countries. [1] While Coumadin and novel oral anticoagulants have been efficient in reducing the stoke risk in patients with atrial fibrillation; there is a subset of patients who are not candidates for anticoagulation.[2] The management of these patients is clinical challenge.We describe a patient with history of permanent atrial fibrillation with contra-indication to anticoagulation presenting with and left atrial thrombus. She was treated with novel generation of epicardial left atrial appendage exclusion device.
Related Concept Videos
Cardiac Catheterization III: Left Heart Catheterization
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
Beats
The Pauli Exclusion Principle
Surface Appendages of Archaea
Anatomy of the Heart

