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Updated: Feb 13, 2026

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Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
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Surgical epicardial left atrial appendage closure:A true alternative
Sacha Salzberg1, Maximillian Emmert2
1HeartClinic, Klinik Hirslanden.
Journal of Atrial Fibrillation
|March 1, 2018
Summary
Early surgical left atrial appendage amputation for stroke prevention had poor outcomes. Modern catheter-based left atrial appendage closure has renewed interest in this minimally invasive stroke risk reduction strategy.
Area of Science:
- Cardiology
- Cardiac Surgery
- Medical Devices
Background:
- Historically, surgical left atrial appendage amputation was performed for stroke prevention.
- This early procedure by Madden in 1949 was highly invasive with suboptimal results.
- Interest shifted away from the left atrial appendage following the development of the Cox-Maze procedure.
Purpose of the Study:
- To review the historical context and evolution of left atrial appendage closure techniques.
- To highlight the resurgence of interest in left atrial appendage closure with modern approaches.
Main Methods:
- Historical review of surgical techniques for left atrial appendage management.
- Discussion of the impact of the Cox-Maze procedure on surgical focus.
- Examination of the advent and influence of catheter-based closure devices.
Main Results:
- The initial surgical approach to left atrial appendage amputation was invasive and associated with poor outcomes.
- The Cox-Maze procedure redirected surgical focus from appendage management.
- Catheter-based left atrial appendage closure has revitalized clinical and research interest in the field.
Conclusions:
- Left atrial appendage closure has evolved significantly from early invasive surgery to modern minimally invasive catheter-based techniques.
- The development of catheter-based options has been pivotal in re-establishing left atrial appendage closure as a key strategy for stroke prevention.
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