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Published on: September 16, 2019
Modeling-based determination of physiological parameters of systemic VOCs by breath gas analysis, part 2
Clemens Ager1, Karl Unterkofler, Pawel Mochalski
1Breath Research Institute, University of Innsbruck, Rathausplatz 4, A-6850 Dornbirn, Austria. Univ.-Clinic for Anesthesia and Intensive Care, Innsbruck Medical University, Anichstr. 35, A-6020 Innsbruck, Austria.
Abstract:
In a recent paper (Unterkofler et al 2015 J. Breath Res. 9 036002) we presented a simple two compartment model which describes the influence of inhaled concentrations on exhaled breath concentrations for volatile organic compounds (VOCs) with small Henry constants. In this paper we extend this investigation concerning the influence of inhaled concentrations on exhaled breath concentrations for VOCs with higher Henry constants. To this end we extend our model with an additional compartment which takes into account the influence of the upper airways on exhaled breath VOC concentrations.
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