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Intravenous Paracetamol Overdose: A Pediatric Case Report
Nagehan Aslan1, Dincer Yildizdas, Didar Arslan
1From the Department of Pediatrics, Division of Pediatric Intensive Care, Cukurova University Faculty of Medicine, Adana, Turkey.
Insights
Intravenous paracetamol overdose in a child caused temporary liver damage due to a dosing error. Prompt recognition and management are crucial for preventing severe adverse events in pediatric patients.
Area of Science:
- Pediatric Medicine
- Clinical Pharmacology
- Toxicology
Background:
- Paracetamol (acetaminophen) is a widely used antipyretic and analgesic in children.
- Increasing use of intravenous (IV) paracetamol necessitates vigilance regarding potential dosing errors.
- Medication errors pose a significant risk in pediatric hospital settings.
Abstract:
Paracetamol is a common antipyretic often used to treat children with fever and pain. With the increasing administration of intravenous (IV) paracetamol, there will be the associated risk of medication dosing errors. We report a case of IV paracetamol overdose in a child with fever during hospital admission. A IV paracetamol dosing error occurred, with delayed recognition resulting in transient hepatotoxicity, with a peak alanine transaminase of 1946 IU/L and aspartate transaminase of 1633 IU/L.
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