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Updated: Feb 13, 2026

A Decellularization Methodology for the Production of a Natural Acellular Intestinal Matrix
Published on: October 7, 2013
Reoperation 7 years after sternal reconstruction with a porcine acellular dermal matrix
Vishal N Shah1,2, Oleg Orlov1,2, Ryan Hoffman3
1Lankenau Institute for Medical Research, Lankenau Medical Center, Wynnewood, PA, USA.
Abstract:
The number of chest wall reconstructions with a biologic mesh is increasing, but its long-term durability is unproven. A 73-year-old man underwent a complex sternal reconstruction 7 years ago with porcine acellular dermal matrix after postoperative repair of his ruptured right ventricle after coronary artery bypass grafting. He recently presented with unstable angina. Cardiac catheterization showed occluded saphenous vein grafts, and the patient required repeat coronary artery bypass grafting. Upon re-entry into the chest, the mesh was completely incorporated into the surrounding tissues and maintained long-term durability.
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