Actual versus 'ideal' antibiotic prescribing for common conditions in English primary care

Koen B Pouwels1,2,3, F Christiaan K Dolk1,2, David R M Smith1

  • 1Modelling and Economics Unit, National Infection Service, Public Health England, London, UK.

Abstract

Insights

Antibiotic overprescribing is common in English primary care, with actual prescription rates far exceeding ideal proportions for many infections, especially respiratory conditions.

Area of Science:

  • General Practice
  • Infectious Diseases
  • Pharmacology

Background:

  • Expert guidelines established ideal antibiotic prescribing proportions for common infectious conditions.
  • Previous work defined optimal antibiotic prescribing benchmarks based on expert consensus.

Purpose of the Study:

  • To compare actual antibiotic prescribing proportions in English primary care with established ideal proportions.
  • To identify specific conditions with the most significant deviations from ideal antibiotic prescribing.

Main Methods:

  • Utilized The Health Improvement Network (THIN) database for 2013-2015.
  • Analyzed antibiotic prescribing proportions for common infectious conditions in acute presentations without comorbidities.
  • Compared observed prescribing rates against expert-defined ideal proportions.

Main Results:

  • Substantially higher antibiotic prescribing proportions were observed than ideal for most conditions.
  • Acute cough consultations saw 41% antibiotic prescriptions versus 10% ideal.
  • Bronchitis (82% vs 13%), sore throat (59% vs 13%), rhinosinusitis (88% vs 11%), and otitis media (92% vs 17%) showed significant overprescribing.
  • Considerable variation in prescribing practices between different general practices was noted.

Conclusions:

  • Significant overprescribing of antibiotics is prevalent in English primary care.
  • Respiratory tract conditions demonstrate the most pronounced antibiotic overprescribing.
  • The findings highlight a critical need to address prescribing patterns to optimize antibiotic use.

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