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Published on: August 30, 2018
Actual versus 'ideal' antibiotic prescribing for common conditions in English primary care
Koen B Pouwels1,2,3, F Christiaan K Dolk1,2, David R M Smith1
1Modelling and Economics Unit, National Infection Service, Public Health England, London, UK.
Objectives:
Previous work based on guidelines and expert opinion identified 'ideal' prescribing proportions-the overall proportion of consultations that should result in an antibiotic prescription-for common infectious conditions. Here, actual condition-specific prescribing proportions in primary care in England were compared with ideal prescribing proportions identified by experts.
Methods:
All recorded consultations for common infectious conditions (cough, bronchitis, exacerbations of asthma or chronic obstructive pulmonary disease, sore throat, rhinosinusitis, otitis media, lower respiratory tract infection, upper respiratory tract infection, influenza-like illness, urinary tract infection, impetigo, acne, gastroenteritis) for 2013-15 were extracted from The Health Improvement Network (THIN) database. The proportions of consultations resulting in an antibiotic prescription were established, concentrating on acute presentations in patients without relevant comorbidities. These actual prescribing proportions were then compared with previously established 'ideal' proportions by condition.
Results:
For most conditions, substantially higher proportions of consultations resulted in an antibiotic prescription than was deemed appropriate according to expert opinion. An antibiotic was prescribed in 41% of all acute cough consultations when experts advocated 10%. For other conditions the proportions were: bronchitis (actual 82% versus ideal 13%); sore throat (actual 59% versus ideal 13%); rhinosinusitis (actual 88% versus ideal 11%); and acute otitis media in 2- to 18-year-olds (actual 92% versus ideal 17%). Substantial variation between practices was found.
Conclusions:
This work has identified substantial overprescribing of antibiotics in English primary care, and highlights conditions where this is most pronounced, particularly in respiratory tract conditions.
Insights
Antibiotic overprescribing is common in English primary care, with actual prescription rates far exceeding ideal proportions for many infections, especially respiratory conditions.
Area of Science:
- General Practice
- Infectious Diseases
- Pharmacology
Background:
- Expert guidelines established ideal antibiotic prescribing proportions for common infectious conditions.
- Previous work defined optimal antibiotic prescribing benchmarks based on expert consensus.
Purpose of the Study:
- To compare actual antibiotic prescribing proportions in English primary care with established ideal proportions.
- To identify specific conditions with the most significant deviations from ideal antibiotic prescribing.
Main Methods:
- Utilized The Health Improvement Network (THIN) database for 2013-2015.
- Analyzed antibiotic prescribing proportions for common infectious conditions in acute presentations without comorbidities.
- Compared observed prescribing rates against expert-defined ideal proportions.
Main Results:
- Substantially higher antibiotic prescribing proportions were observed than ideal for most conditions.
- Acute cough consultations saw 41% antibiotic prescriptions versus 10% ideal.
- Bronchitis (82% vs 13%), sore throat (59% vs 13%), rhinosinusitis (88% vs 11%), and otitis media (92% vs 17%) showed significant overprescribing.
- Considerable variation in prescribing practices between different general practices was noted.
Conclusions:
- Significant overprescribing of antibiotics is prevalent in English primary care.
- Respiratory tract conditions demonstrate the most pronounced antibiotic overprescribing.
- The findings highlight a critical need to address prescribing patterns to optimize antibiotic use.
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