Related Experiment Video
Updated: Feb 13, 2026

Isolation, Identification, and Purification of Murine Thymic Epithelial Cells
Published on: August 8, 2014
In situ evidence of cellular senescence in Thymic Epithelial Cells (TECs) during human thymic involution
Alexandra Barbouti1, Konstantinos Evangelou2, Ioannis S Pateras3
1Department of Anatomy-Histology-Embryology, Medical School, University of Ioannina, Ioannina, Greece.
Abstract:
Cellular senescence, an age-related process in response to damage and stress, also occurs during normal development and adult life. The thymus is a central lymphoepithelial organ of the immune system that exhibits age-related changes termed thymic involution. Since the mechanisms regulating thymic involution are still not well elucidated, we questioned whether cellular senescence is implicated in this process. We demonstrate, for the first time in situ, that cellular senescence occurs during human thymic involution using SenTraGor™, a novel chemical compound that is applicable in archival tissue material, providing thus further insights in thymus histophysiology.
More Related Videos
09:41Preparation of Single-Cell Suspension of Mouse Thymic Epithelial Cells and Staining of Intracellular Molecules for Flow Cytometric AnalysisMechanisms
Published on: July 26, 2024
08:02Promoting 3-D Aggregation of FACS Purified Thymic Epithelial Cells with EAK 16-II/EAKIIH6 Self-assembling Hydrogel
Published on: June 27, 2016
Related Concept Videos
The Evidence for Evolution
Replicative Cell Senescence
Cellular Differentiation
A zygote is a...
Cellular Respiration
In-situ Hybridization
Types of probes and labels
A probe is a complementary strand of DNA or RNA that binds to corresponding nucleotide sequences in a cell. Many...
Epithelial Tissues and Their Functions
Epithelial tissues provide the body's first line of protection from physical,...