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Updated: Feb 13, 2026

An In Vivo Mouse Model of Total Intravenous Anesthesia During Cancer Resection Surgery
Published on: June 8, 2021
Survival and functional and oncological outcomes following intersphincteric resection for low rectal cancer:
Călin Molnar1, Butiurca Vlad-Olimpiu2, Botoncea Marian2
11 Head of Surgery, University of Medicine and Pharmacy, Tîrgu-Mureș, Mureș County, Romania.
Abstract:
Objective This study was performed to evaluate the 1-year survival rate and functional outcomes of 20 patients who underwent intersphincteric resection (ISR) for low rectal cancer. Methods Twenty patients who underwent ISR for low rectal cancer were followed up for 1 year. Complications, functional outcomes objectified by the Wexner score, and oncological outcomes were assessed. Results The short-term survival rate was 100%. The median Wexner score was ≤10 in all patients at 12 months after surgery. Signs of local recurrence were absent, and antigen levels remained within the reference ranges 1 year postoperatively. Conclusions ISR is a feasible alternative in highly selected patients who primarily refuse a colostomy bag and present with type II or III tumors. In the present study, patient-reported continence was satisfactory, and the absence of a colostomy bag increased patients' quality of life. The oncological outcomes were satisfactory at 1 year postoperatively.
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