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Identifying trial recruitment uncertainties using a James Lind Alliance Priority Setting Partnership - the PRioRiTy
Patricia Healy1,2, Sandra Galvin3,4, Paula R Williamson5
1Health Research Board - Trials Methodology Research Network, Galway, Ireland. Patricia.healy@nuigalway.ie.
Trials
|March 2, 2018
Summary
This study prioritized research questions to improve recruitment for randomized trials. Key findings emphasize integrating trials into routine care and enhancing participant communication and involvement.
Area of Science:
- Clinical trial methodology
- Health services research
- Patient and public involvement in research
Background:
- Inadequate recruitment hinders randomized trials, necessitating evidence-based strategies.
- The PRioRiTy study aimed to identify and prioritize unanswered questions in trial recruitment.
- A Priority Setting Partnership (PSP) involved diverse stakeholders, including the public, healthcare professionals, and researchers.
Framework:
- The study employed an eight-stage Priority Setting Partnership (PSP) process.
- This involved stakeholder engagement, uncertainty collation, and question refinement.
- The James Lind Alliance facilitated the partnership's structured approach.
Implementation:
- 790 survey respondents generated 1693 open-text answers, identifying 1880 potential research questions.
- After merging and filtering, 31 unique questions were confirmed as unanswered.
- A face-to-face workshop prioritized the top 10 questions, with the highest ranked question focusing on integrating trials into routine care.
Implications:
- Prioritized questions highlight the need to normalize trials within clinical care pathways.
- Enhancing communication, addressing participation barriers, and increasing public involvement are crucial.
- This research provides a roadmap for future trial recruitment strategies.
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