Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Methods of Obtaining Topography01:25

Methods of Obtaining Topography

332
Topography involves measuring and mapping land elevations, natural features, and artificial structures to create accurate representations of the terrain. Topographic surveying relies on traditional and modern methods, each with distinct advantages and limitations.Traditional Surveying Methods:Transit stadia surveys and plane table surveys were widely used traditional surveying methods. These techniques relied on instruments like theodolites and stadia rods for measuring distances and angles,...
332
Cell-surface Signaling01:21

Cell-surface Signaling

54.8K
Hormones—or any molecule that binds to a receptor, known as a ligand—that are lipid-insoluble (water-soluble) are not able to diffuse across the cell membrane. In order to be able to affect a cell without entering it, these hormones bind to receptors on the cell membrane. When a first messenger, a hormone, binds to a receptor, a signal cascade is set off, causing second messengers, proteins inside the cell, to become activated, resulting in downstream effects.
54.8K
Surface Tension and Surface Energy01:16

Surface Tension and Surface Energy

3.3K
When a paint brush is immersed in water, the bristles wave freely inside the water. When it is taken out, the bristles stick together. The reason behind this effect is surface tension.
Consider a beaker filled with liquid. The bulk molecules in the liquid experience equal attractive forces on all sides with the surrounding molecules. However, the surface molecules experience a net attractive force downward due to the bulk molecules. The surface of the liquid behaves like a stretched membrane,...
3.3K
Wood Surfacing01:14

Wood Surfacing

367
Wood surfacing is a critical finishing process designed to smoothen the wood surface, enhance its dimensional accuracy, and make handling safer. This process compensates for potential shrinkage during the seasoning phase by marginally increasing the wood dimensions before surfacing. It also helps correct some distortions that may occur as the wood dries.
The equipment used in the surfacing process is a plane equipped with rotating blades. This tool efficiently smoothens the wood surface and can...
367
Area of a Surface of Revolution01:29

Area of a Surface of Revolution

71
Surfaces of revolution are formed when a two-dimensional curve is rotated around an axis, producing a three-dimensional shape. This concept is used in engineering tasks like determining the surface area of a rocket nozzle, where precise calculations are critical for applying uniform heat-resistant coatings. When a curve is revolved about the x-axis, it sweeps out a continuous surface whose area must be calculated accurately to estimate material requirements.Approximating with Conical BandsTo...
71
Surface Appendages of Archaea01:23

Surface Appendages of Archaea

691
Archaeal surface appendages are highly specialized structures essential for environmental adaptation, encompassing roles in adhesion, biofilm formation, and motility. Among these appendages, pili and archaella stand out for their distinct morphologies and functionalities, enabling archaea to thrive in diverse and often extreme environments.Pili: Adhesion and Biofilm FormationPili are filamentous structures assembled from pilin protein subunits, primarily contributing to adhesion and biofilm...
691

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toward Light-Responsive Hydrogel-Based Valves for Flow Regulation.

Langmuir : the ACS journal of surfaces and colloids·2026
Same author

Engineered Strain in 2D Materials by Direct Growth on Deterministically Patterned Grayscale Topographies.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Amide-Forming Ligations at Physiological pH for the Encapsulation of Human Mesenchymal Stem Cells.

Biomacromolecules·2026
Same author

Substitution of human olfaction by the trigeminal system.

Science advances·2025
Same author

Fabrication of self-emulsifying lipid microstructure by stiffness-tunable mold for drug delivery applications.

Microsystems & nanoengineering·2025
Same author

Colorimetric point-of-care diagnostic to monitor <i>Enterococcus faecalis</i> causing urinary tract infection.

Journal of materials chemistry. B·2025
Same journal

In situ imaging of proximal biomolecules via Proximity Anchored Modules Assembly.

Journal of nanobiotechnology·2026
Same journal

Single-cell transcriptomics-guided dynamic hydrogel delivery of artemisia argyi-derived EVs relieves ER stress and promotes diabetic wound regeneration.

Journal of nanobiotechnology·2026
Same journal

Self-assembling pH-responsive peptide nanoparticles delivering pyrvinium pamoate induce osteosarcoma senescence through CBX4 ubiquitination-mediated inhibition of YAP1 SUMOylation.

Journal of nanobiotechnology·2026
Same journal

Enzyme-enhanced albumin-stabilized nanopolymers for cascade catalysis-driven ferroptosis-immunotherapy.

Journal of nanobiotechnology·2026
Same journal

A bioadhesive antioxidant dual-crosslinked hydrogel mitigates endothelial pyroptosis to enhance ischemic flap survival.

Journal of nanobiotechnology·2026
Same journal

Targeting tumor-associated bacteria in digestive system cancers: carcinogenic mechanisms and nano-regulate platform design.

Journal of nanobiotechnology·2026
See all related articles

Related Experiment Video

Updated: Feb 13, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

4.0K

Nanostructured surface topographies have an effect on bactericidal activity.

Songmei Wu1, Flavia Zuber2, Katharina Maniura-Weber2

  • 1School of Science, Beijing Jiaotong University, No. 3 Shangyuancun, Haidian District, Beijing, 100044, People's Republic of China. smwu@bjtu.edu.cn.

Journal of Nanobiotechnology
|March 2, 2018
PubMed
Summary
This summary is machine-generated.

Nanostructured polymer surfaces with specific pillar densities and heights show high bactericidal efficiency against Staphylococcus aureus. Optimized surface topography is key to developing effective antibacterial surfaces and combating antimicrobial resistance.

Keywords:
Antibacterial surfaceBactericidal activityNanoscale topographyNanostructure

More Related Videos

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering
12:22

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Published on: March 1, 2016

8.7K
ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
16:33

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly

Published on: April 17, 2014

13.0K

Related Experiment Videos

Last Updated: Feb 13, 2026

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro
11:52

Evaluation of Antimicrobial Activities of Nanoparticles and Nanostructured Surfaces In Vitro

Published on: April 21, 2023

4.0K
Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering
12:22

Preparation of Thermoresponsive Nanostructured Surfaces for Tissue Engineering

Published on: March 1, 2016

8.7K
ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly
16:33

ECM Protein Nanofibers and Nanostructures Engineered Using Surface-initiated Assembly

Published on: April 17, 2014

13.0K

Area of Science:

  • Materials Science
  • Biophysics
  • Nanotechnology

Background:

  • Antimicrobial resistance necessitates alternatives to antibiotics.
  • Biophysical manipulation of surface topography offers a promising approach to prevent bacterial adhesion.
  • Understanding the relationship between surface features and antibacterial properties is crucial for developing effective antibacterial surfaces.

Purpose of the Study:

  • To systematically investigate the topographical effects on the bactericidal activity of nanostructured surfaces.
  • To identify optimal surface parameters for maximizing antibacterial efficacy.
  • To develop a biophysical model explaining bacterial interaction with nanostructures.

Main Methods:

  • Fabrication of nanostructured Ormostamp polymer surfaces using nano-replication technology.
  • Creation of nanopillar arrays with varying densities (20-70 pillars/μm²) and heights.
  • Testing bactericidal efficiency against Staphylococcus aureus on surfaces with roughness ranging from 3.1 to 39.1 nm.

Main Results:

  • Surfaces with an average pillar density of ~40 pillars/μm² and roughness of 39.1 nm achieved nearly 100% bactericidal efficiency.
  • Flat control surfaces showed only 20% bactericidal efficiency.
  • High ( ~70 pillars/μm²) and low (<20 pillars/μm²) pillar densities, with roughness <20 nm, significantly reduced bactericidal efficacy.

Conclusions:

  • Surface topography, including pillar density and height, significantly impacts bacterial cell membrane adhesion and stretching.
  • Optimized nanostructure design is critical for developing highly effective antibacterial surfaces.
  • A biophysical model can interpret bacterial morphological changes on nanostructured surfaces.