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Association between psoriasis and asthma risk: A meta-analysis.
Jian Wang1, Rui Ke, Wenhua Shi
1Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, P.R. China.
Allergy and Asthma Proceedings
|March 2, 2018
Summary
This meta-analysis confirms psoriasis is linked to a higher risk of asthma. Older individuals with psoriasis face an even greater susceptibility to developing asthma.
Area of Science:
- Dermatology
- Pulmonology
- Epidemiology
Background:
- Psoriasis is a chronic inflammatory skin condition.
- Previous studies suggest a link between psoriasis and asthma, but findings are inconsistent.
Purpose of the Study:
- To conduct a meta-analysis to determine if psoriasis increases the risk of asthma.
Main Methods:
- A comprehensive literature search was performed up to May 2017.
- Pooled odds ratios (OR) and 95% confidence intervals (CI) were calculated.
Main Results:
- Six studies (66,772 psoriasis cases, 577,415 controls) were analyzed.
- Psoriasis significantly increased asthma risk (OR 1.32 [95% CI, 1.20-1.46]).
- Older patients (≥50 years) with psoriasis showed higher asthma risk (OR 1.64) compared to younger patients (OR 1.25).
- Significant asthma risk increases were observed in Asian (OR 1.35) and white (OR 1.27) populations with psoriasis.
Conclusions:
- Psoriasis is associated with increased asthma susceptibility.
- Older individuals with psoriasis are particularly at higher risk for asthma.
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