Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Epigenetic Regulation01:46

Epigenetic Regulation

33.9K
Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
33.9K
Epigenetic Regulation01:37

Epigenetic Regulation

3.9K
Epigenetic changes alter the physical structure of the DNA without changing the genetic sequence and often regulate whether genes are turned on or off. This regulation ensures that each cell produces only proteins necessary for its function. For example, proteins that promote bone growth are not produced in muscle cells. Epigenetic mechanisms play an essential role in healthy development. Conversely, precisely regulated epigenetic mechanisms are disrupted in diseases like cancer.
X-chromosome...
3.9K
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

1.2K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.2K
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

2.5K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
2.5K
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

1.2K
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
1.2K
Alzheimer's Disease: Treatment01:22

Alzheimer's Disease: Treatment

981
Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...
981

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same journal

Mechanistic insights into PM<sub>2.5</sub>-induced cardiac fibrosis involving ERS/TXNIP/NLRP3-driven pyroptosis in multiple cell types.

Environmental epigenetics·2026
Same journal

Characterization of long noncoding RNAs, microRNAs, and piwiRNAs in reef-building corals.

Environmental epigenetics·2026
Same journal

BPA-induced differential methylation of the androgen receptor promoter CpG island in medaka germline and somatic cells.

Environmental epigenetics·2026
Same journal

Persistent transcriptomic changes following repeated exposure to wood smoke in nonhuman primate airway epithelial cells.

Environmental epigenetics·2026
Same journal

Prenatal humid heat exposure and cord blood extracellular vesicle microRNA profiles in a Ghanaian Pregnancy Cohort: GRAPHS.

Environmental epigenetics·2026
Same journal

DNA methylation mediates the multiple sclerosis onset risk associated with HHV-6 DNA positivity.

Environmental epigenetics·2026

Related Experiment Video

Updated: Feb 13, 2026

An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling
08:34

An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling

Published on: December 18, 2017

7.0K

Epigenetics in disease and well-being.

Rodriguez-Martinez Heriberto1

  • 1Department of Clinical and Experimental Medicine (IKE), Linköping University, Linköping, Sweden.

Environmental Epigenetics
|March 2, 2018
PubMed
Summary

Environmental factors can trigger epigenetic changes, impacting health across generations. This research explores these mechanisms and proposes epigenomic-based preventative medicine for human and animal well-being.

Keywords:
Linköping Universitydisease and well-beingenvironmentepigenetic misregulationresearch seminarstress

More Related Videos

ATAC-Seq Optimization for Cancer Epigenetics Research
07:13

ATAC-Seq Optimization for Cancer Epigenetics Research

Published on: June 30, 2022

5.4K
In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
10:44

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing

Published on: May 5, 2023

1.9K

Related Experiment Videos

Last Updated: Feb 13, 2026

An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling
08:34

An Engineered Split-TET2 Enzyme for Chemical-inducible DNA Hydroxymethylation and Epigenetic Remodeling

Published on: December 18, 2017

7.0K
ATAC-Seq Optimization for Cancer Epigenetics Research
07:13

ATAC-Seq Optimization for Cancer Epigenetics Research

Published on: June 30, 2022

5.4K
In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
10:44

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing

Published on: May 5, 2023

1.9K

Area of Science:

  • Environmental epigenetics
  • Transgenerational inheritance
  • Preventative medicine

Background:

  • Epigenetic modifications link environmental factors to health outcomes.
  • Environmental stressors can disrupt homeostasis, leading to transgenerational effects.
  • Understanding these mechanisms is crucial for health and disease research.

Purpose of the Study:

  • To discuss the interaction between environmental factors and epigenetic modifications.
  • To explore the consequences for human and animal health.
  • To propose epigenomic-based pre-emptive medicine.

Main Methods:

  • Review of presented papers from a research education seminar.
  • Highlighting mechanisms of environmental stress on homeostasis.
  • Discussion of epigenomic-based strategies.

Main Results:

  • Environmental stressors can induce transgenerational epigenetic effects.
  • The study identified pathways through which environmental challenges impact health.
  • Potential for epigenomic markers in predicting and preventing disease.

Conclusions:

  • Epigenetic mechanisms mediate the impact of environmental factors on health.
  • Transgenerational effects of environmental stressors are a significant concern.
  • Epigenomic-based pre-emptive medicine offers a novel approach to health management.