Related Experiment Video
Updated: Feb 13, 2026
05:52
Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
Published on: August 19, 2021
13.5K
Completion lymphadenectomy for sentinel node positive cutaneous head & neck melanoma.
Cecelia E Schmalbach1, Carol R Bradford2
1Department of Otolaryngology-Head & Neck Surgery Indiana University School of Medicine, Roudebush VA Medical Center Indianapolis Indiana U.S.A.
Laryngoscope Investigative Otolaryngology
|March 2, 2018
Summary
For head and neck melanoma patients with a positive sentinel lymph node biopsy (SLNB), completion lymph node dissection (CLND) may not be necessary. This review examines the evidence for discontinuing CLND after a positive SLNB.
Area of Science:
- Oncology
- Dermatology
- Surgical Pathology
Background:
- Sentinel lymph node biopsy (SLNB) for melanoma has evolved from staging to potential therapy.
- The necessity of completion lymph node dissection (CLND) after a positive SLNB is under active investigation.
Purpose of the Study:
- To review the current evidence regarding the utility of CLND in head and neck cutaneous melanoma patients with a positive SLNB.
- To provide an evidence-based assessment of whether CLND is required following a positive SLNB.
Main Methods:
- Systematic review of recent large, multi-institutional randomized trials.
- Evidence-based analysis of contemporary literature on SLNB and CLND in head and neck melanoma.
Main Results:
- Focus on outcomes and necessity of CLND following positive SLNB.
- Analysis of data from randomized trials addressing CLND after positive SLNB.
Conclusions:
- The role of CLND in SLNB-positive head and neck melanoma requires careful consideration based on current evidence.
- This review aims to guide clinical decision-making regarding CLND for these patients.
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