Analysis of a Minimally Invasive Intracranial Pressure Signals During Infusion at the Subarachnoid Spinal Space of

G Frigieri1, R A P Andrade2, C C Wang2

  • 1Braincare, São Carlos, SP, Brazil. g.frigieri@gmail.com.

Abstract

Insights

A new minimally invasive intracranial pressure monitoring (ICPMI) method shows promising results. It accurately reflects both the trend and pulsatile components of intracranial pressure compared to invasive methods.

Area of Science:

  • Biomedical Engineering
  • Neurosurgery
  • Medical Devices

Background:

  • Intracranial pressure monitoring (ICPMI) is crucial for managing neurological conditions.
  • Traditional invasive ICP monitoring carries risks.
  • A minimally invasive alternative is needed.

Purpose of the Study:

  • To validate a novel minimally invasive ICPMI method.
  • To compare ICPMI with invasive ICP monitoring (ICPInv).
  • To assess both trend and pulsatile components of the ICP signal.

Main Methods:

  • Simultaneous ICP monitoring in an anesthetized pig model using ICPMI and ICPInv.
  • ICP elevation via controlled saline infusions.
  • Signal decomposition into trend and pulsatile components for correlation analysis.

Main Results:

  • The pulsatile components of ICPMI and ICPInv showed correlation coefficients above 0.5.
  • Signal trends from ICPMI demonstrated good agreement with ICPInv (correlation > 0.5).
  • High correlation was maintained throughout the infusions.

Conclusions:

  • The minimally invasive ICPMI method shows good linear agreement for signal trends.
  • Waveform analysis of the pulsatile component suggests ICPMI can assess patient neuroclinical status.
  • ICPMI offers a viable alternative to invasive ICP monitoring.

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