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Related Concept Videos

Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

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Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...
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Thoracic Aorta01:15

Thoracic Aorta

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The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
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Induced Pluripotent Stem Cells01:13

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Stem cells are undifferentiated cells that divide and produce different types of cells. Ordinarily, cells that have differentiated into a specific cell type are post-mitotic—that is, they no longer divide. However, scientists have found a way to reprogram these mature cells so that they “de-differentiate” and return to an unspecialized, proliferative state. These cells are also pluripotent like embryonic stem cells—able to produce all cell types—and are therefore...
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Adult Stem Cells01:33

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Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
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Psychodynamic Perspectives on Personality01:27

Psychodynamic Perspectives on Personality

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The psychodynamic perspective in psychology asserts that most personality functions operate unconsciously, outside of awareness. This means that the motives and emotions driving behavior often remain hidden, automatically buried in the unconscious mind as a defense mechanism to shield us from psychological distress. According to this theory, the unconscious mind contains thoughts, memories, and emotions that are too disturbing to face directly.
Psychodynamic theorists argue that unconscious...
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Embryonic Stem Cells00:58

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Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
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Related Experiment Video

Updated: Feb 13, 2026

Electromagnetic Navigation Transthoracic Nodule Localization for Minimally Invasive Thoracic Surgery
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Stem Cells Application in Thoracic Surgery: Current Perspective and Future Directions.

Francesco Petrella1,2, Lorenzo Spaggiari3,4

  • 1Department of Thoracic Surgery, European Institute of Oncology, Milan, Italy. francesco.petrella@ieo.it.

Advances in Experimental Medicine and Biology
|March 2, 2018
PubMed
Summary
This summary is machine-generated.

Stem cell therapies offer two key thoracic surgery applications: regenerative medicine for healing and stem cells as vectors for targeted cancer drug delivery. These approaches show promise in treating conditions like bronchopleural fistula and mesothelioma.

Keywords:
Drug loading and deliveryRegenerative medicineStem cells

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Area of Science:

  • Clinical applications of stem cell technologies in thoracic surgery.
  • Focus on regenerative medicine and drug delivery for thoracic oncology.

Background:

  • Bronchopleural fistula, a post-lung resection complication, can be addressed by stem cells promoting bronchial healing.
  • Mesenchymal stem cells (MSCs) show potential for targeted anti-cancer drug delivery in thoracic oncology, particularly for malignant mesothelioma.

Purpose of the Study:

  • To review clinical applications of stem cell technologies in thoracic surgery.
  • To emphasize regenerative medicine and drug loading/delivery aspects in thoracic oncology.

Main Methods:

  • Review of existing literature on stem cell applications in thoracic surgery.
  • Focus on regenerative medicine and drug delivery strategies.

Main Results:

  • Stem cells are explored for regenerative medicine to restore function and as vectors for targeted drug delivery.
  • Potential for stem cells in treating bronchopleural fistula and malignant mesothelioma.

Conclusions:

  • Stem cell technologies present significant clinical potential in thoracic surgery.
  • Regenerative medicine and targeted drug delivery using stem cells are promising avenues for thoracic conditions.