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Spinal Peripheral Primitive Neuroectodermal Tumors: A Radiological Analysis of Ten Cases
Xiaoping Yi1, Moling Zhou, Shenghui Liao
1Central South University, Xiangya Hospital, Department of Radiology, Changsha, Hunan Province, China.
Turkish Neurosurgery
|March 2, 2018
Summary
Imaging features of spinal peripheral primitive neuroectodermal tumors (spPNET) were summarized. These tumors often appear as well-defined masses with heterogeneous enhancement, aiding in diagnosis.
Area of Science:
- Neuro-oncology
- Radiology
- Pathology
Background:
- Spinal peripheral primitive neuroectodermal tumors (spPNET) are rare neoplasms.
- Accurate diagnosis relies on characteristic imaging findings.
Purpose of the Study:
- To delineate the computed tomography (CT) and magnetic resonance imaging (MRI) features of spPNET.
- To correlate imaging findings with clinicopathological data.
Main Methods:
- Retrospective analysis of CT and MRI scans from 10 spPNET patients.
- Review of clinicopathological data, including Ki-67 expression.
Main Results:
- spPNETs typically present as heterogeneous, isointense lesions with avid, heterogeneous enhancement.
- Extradural lesions showed "vault wall-like growth," linear enhancement, and bone involvement.
- Intradural extramedullary lesions often exhibited ring enhancement.
- Tumor necrosis, bone destruction, and hemorrhage correlated with high Ki-67 expression.
Conclusions:
- A well-defined spinal mass with isointensity/attenuation and heterogeneous enhancement is suggestive of spPNET.
- spPNET should be considered in the differential diagnosis of spinal tumors with these imaging characteristics.
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